Results 311 to 320 of about 3,590,044 (385)
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
STFM Launches Professionalism in Family Medicine Education Initiative. [PDF]
Theobald M.
europepmc +1 more source
Regional Nursing Students Conference 2017 : Nurses at the forefront transforming care (Programme & Abstract) [PDF]
Universiti Malaysia Sarawak, Faculty of Medicine and Health Sciences
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Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Correction: Park et al. Protective Effects of Nargenicin A1 against Tacrolimus-Induced Oxidative Stress in Hirame Natural Embryo Cells. <i>Int. J. Environ. Res. Public Health</i> 2019, <i>16</i>, 1044. [PDF]
Park C+12 more
europepmc +1 more source
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns+4 more
wiley +1 more source
CMPH Bulletin, Issue 5, July 2018 [PDF]
Universiti Malaysia Sarawak, Faculty of Medicine and Health Sciences
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Correction: Applications of equity frameworks in theory-based health behavior interventions: a scoping review. [PDF]
Gallagher KS+5 more
europepmc +1 more source