Maternal Perceptions and Practices in Trachoma Prevention: A Descriptive and Correlational Analysis Using the Health Belief Model in Rural Ethiopia. [PDF]
Asmare ZA +19 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A cross-sectional examination of immune adaptations during pregnancy in the ECHO Cohort. [PDF]
Banker SM +12 more
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The George Washington University School of Medicine and Health Sciences
openaire +5 more sources
Cutting edge reviews: Battling one Neglected Tropical Disease after another. [PDF]
Pappas G, Brindley PJ, Kamhawi S.
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Response to the Union's statement on ongoing conflicts and impact on health services. [PDF]
Ahmad Khan F +35 more
europepmc +1 more source
Aligning action across major infectious diseases in a dynamic global health landscape. [PDF]
Ford N, Kasaeva T.
europepmc +1 more source
Correction: Rehman et al. Analysis of Consensus Molecular Subtypes of Colorectal Cancer in Oman with Clinicopathologic Correlation. <i>Int. J. Mol. Sci.</i> 2026, <i>27</i>, 2038. [PDF]
Rehman S +9 more
europepmc +1 more source

