Results 61 to 70 of about 4,061,969 (303)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
EVIDENCE-BASED MEDICINE – I. GENERAL PRINCIPLES
Zdravniški Vestnik, 2003 Background. Evidence-based medicine is a method that helps physicians find and critically evaluate evidences from the medical literature, and apply the evidences in clinical decision-making. In clinical practice the method supplements core medical skills,
Angela Čuk
doaj
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The Development of Narrative Practices in Medicine c.1960-c.2000 [PDF]
, 2015 ‘… if I have to explain to someone, like the anthropologist from Mars, what any of these words like compassion or whatever is, sooner or later I have to tell them a story.’ Professor Arthur Frank Chaired by Professor Brian Hurwitz (King’s College), this ...
JONES, EM
core
Adherence to non-selective beta blockers for prevention of variceal bleeding in cirrhotic patients
, 2021 Background and Aim: Long-term use of non-selective beta blockers (NSBBs) is essential for the prevention of esophageal variceal bleeding in liver cirrhosis but may impair the patient’s adherence.
Ren, Tianshu +7 more
core +1 more source
Diagnosis and Treatment Protocol for COVID-19 Patients (Tentative 9th Version)
Infectious Diseases & Immunity, 2022 The General Office of National Health Commission & the General Office of National Administration of Traditional Chinese Medicine +1 more
doaj +1 more source
Journal of the Royal Army Medical Corps, 2004 A J, Moore, M, Dayer, E, Swallow
openaire +2 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source