FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Clinical Decision Support and Natural Language Processing in Medicine: Systematic Literature Review. [PDF]
J Med Internet ResEguia H +4 more
europepmc +1 more source
An Analysis of the Top-cited Articles in Emergency Medicine Education Literature. [PDF]
West J Emerg Med, 2017 Munzer BW +7 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Mood disorders and complementary and alternative medicine: a literature review. [PDF]
Neuropsychiatr Dis Treat, 2013 Qureshi NA, Al-Bedah AM.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Evidence-Based Practice for the Use of pH Indicator Paper Strip in Oral Medicine: A Literature Review. [PDF]
CureusShamsi-Basha B +5 more
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Patient compliance based on genetic medicine: a literature review. [PDF]
J Community Genet, 2014 Schneider KI, Schmidtke J.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature review. [PDF]
Comput Struct Biotechnol JBardini R, Di Carlo S.
europepmc +1 more source