Results 131 to 140 of about 2,199,020 (293)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Aesthetic Medicine Procedures in Cancer Survivors – A Literature Review

Journal of Education, Health and Sport
Background: Advances in oncology have significantly increased long-term survival rates, creating a growing need to manage persistent physical and psychosocial consequences of treatment in cancer survivors, including scarring, alopecia, pigmentation ...
Katarzyna Skibicka, Albert Jaśniak, Weronika Wesołowska, Jarosław Pietrzak   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

TRASTORNOS DEL ESTADO DE ÁNIMO EN CIEN AÑOS DE SOLEDAD. Ilustración mediante un caso clínico

Medicina, 2011
<p><strong>RESUMEN</strong> </p><table width="100%" border="0" cellspacing="0" cellpadding="0"><tbody><tr><td valign="top" width="79%"><p><span style="color: #000000;">En la novela Cien Años de ...
Álex González Grau
doaj  

Applications of MDMA in Modern Medicine - A Literature Review

Journal of Education, Health and Sport
MDMA or 3,4- methylenedioxymethamphetamine is a psychoactive substance, exhibiting mild hallucinogenic properties, that became widely known as a recreational party drug.
Wiktoria Podlasiewicz, Paweł Siudziński, Mateusz Łyko, Alicja Skoczylas, Jakub Kurasz, Wojciech Maj, Wiktoria Tomaszewska, Katarzyna Pala, Piotr Dudziak, Anna Nowak, Maria Golińska   +10 more
doaj   +1 more source

TRAVEL MEDICINE PRACTICE, EDUCATION AND RESEARCH IN BRAZIL – CURRENT STATE AND FUTURE PERSPECTIVES

, 2015
Objective: Travel medicine services and training are well established in the British Isles, but the situation in Brazil has not been extensively described. Methodology: We conducted a review of literature related to travel to travel medicine services and
Cardoso Oliveira, Fernando, Schultz de Souza, Afonso, Flaherty, Gerard   +2 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Excellent Response to Anti-PD1 therapy in a Patient with Hepatocellular Carcinoma: Case Report and Review of Literature

, 2017
Hepatocellular carcinoma (HCC) is an aggressive cancer associated with high mortality worldwide. HCC develops in the setting of underlying cirrhosis due to chronic liver disease.
Wu, Howard, Sehdev, Amikar, Mamdani, Hirva, O'Neil, Bert H.   +3 more
core   +1 more source

Medicine and literature

Acta Médica del Centro, 2014
Throughout  the humanity's evolution the medicine and the literature have been bound. This work is a tight synthesis on the topic, without exciting doubts for all those that consider  the medicine like an art.
openaire   +1 more source

Clinical Guidelines for Diagnosis and Treatment of Knee Osteoarthritis(Xibibing)in Orthopedics and Traumatology of Traditional Chinese Medicine

, 2019
Knee osteoarthritis(KOA, Xibibing)is a common disease in people over 40, and the disability rate is 53%.Based on evidence-based medicine, the clinical practice guidelines of traditional Chinese medicine(TCM)for Xibibing(KOA), it is necessary to ...
Working Group on Setting up Guidelines for Diagnosis and Treatment of Knee Osteoarthritis (Xibibing) in Orthopedics Section of China Association of Chinese Medicine
core   +1 more source