Results 101 to 110 of about 65,612 (263)

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

The effectiveness of a Kampo e-learning course incorporated into the medical education curriculum: a possible solution to instructor shortages and time constraints

BMC Medical Education
Background The shortage of instructors and time to teach traditional Japanese (Kampo) medicine (KM) limits students’ understanding of its usefulness. We developed an e-learning course to solve this problem. Methods The Kampo e-learning course consists of
Yoshinobu Nakada, Makoto Arai, Ippei Yamato, Tatsuya Nogami, Hiroshi Odaguchi, Daigo Taniguchi, Jun Tomita, Tomoaki Ishigami   +7 more
doaj   +1 more source

Non-referral of potential organ donors in South Africa: insights, challenges and ethical dilemmas

The Pan African Medical Journal, 2018
Traditionally, minimal potential organ donor referrals emanate from general medicine departments. We use a clinical vignette to draw attention to challenges related to referral of potential organ donors from general internal medicine departments.
Poobalan Naidoo, Harriet Rosanne Etheredge, Virendra Rambiritch, Akira Singh, Scott Mahoney, Vanesha Naidu   +5 more
doaj   +1 more source

Ethical Issues in Radioisotope Shortages: Rationing and Priority Setting

, 2010
In recent years, shortages of radioisotopes that cannot be stockpiled have created a scenario in which they may be considered, periodically, a scarce medical resource.
M. S. Rosenthal, Rosenthal, M Sara
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Drug Shortage and Ethical Issues: Integrating Multidisciplinary Perspectives with a Shared Ethical Framework

Pharmacy
Drug shortages can cause ethical dilemmas when no systematic, equitable allocation, or utilization schema is in place. During the COVID-19 pandemic, an ethical framework outlining moral values was proposed as way to approach allocating limited resources ...
Maya C. Wai
doaj   +1 more source

Medicine shortage: Serbian experience

Book of Abstracts - International congress Public health – achievements and challenges - zbornik radova
Background: The unavailability of medicines continues to be on the rise in Europe and it has a tremendous impact on patients. Medicine shortages occur across all healthcare settings and involve both essential life-saving medicines and very commonly used medicines.
Nataša Jaćović-Knežević, Dragana Atanasijević   +1 more
openaire   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Designing Supply Chain Network Resilience : Medicine Shortages in the Pharmaceutical Industry

, 2021
Background: In a globalised world and increased interconnected business environments effective resilience capabilities are pivotal for disruption mitigation.
Wagenknecht, Imke, Barfuß, Julia
core  

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source