Results 111 to 120 of about 1,058,319 (317)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Are Student Attitudes Toward Family Medicine Research Associated With Family Medicine Career Choice at the Individual Level? [PDF]

, 2023
Daniel J. Parente
openalex   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Niklas Luhmann’s Systems Theory and the challenges involved for legally achieving the of right to health in regard to medicines - DOI: 10.3395/reciis.v1i2.93en

RECIIS, 2007
This essay deals with some of the limits and risks related to the essential performance of the judiciary in the control of the public medicine supply in defence of the right to health and dignity of the human being. This question relates to the necessity
Marcus Orione Gonçalves Correia, Renato Negretti Cruz   +1 more
doaj  

LIMULUS - PAST, PRESENT AND FUTURE [PDF]

Medicamentul Veterinar, 2016
Related rather to spider and scorpion, these blue-blooded, forgotten by time, Horseshoe crab own some of the most interesting secrets. This shellfish has survived on Earth for millions of years 562/450, without suffering major changes.
Alina Draghici, Simona Sturzu, Daniela Tirsinoaga, Mariana Dumitrache, Andreea Maftei   +4 more
doaj  

תערוכה. היהודים בתולדות הרפואה. קטלוג Exhibition. Jews in the History of Medicine. Catalogue

, 2020

openalex   +1 more source

Foot Care Knowledge Assessment among Type 2 Diabetic Patients attending Three Family Medicine Centers in Cairo [PDF]

, 2017
Diaa Marzouk, Nesrine A Mohamed, Dalia Sos, Nouran Fakkar Hammam Fakkar, M. Diaa, A Ogbera, O Fasanmade, A Ohwovoriole, O Adediran, J Apelgvist, J Larsson, D Tessier, L Vague, E Hokkam, H George, P Rakesh, Krishna, Alex Abraham, V George, K Prasad, J, S Hasnain, N Sheikh, M El-Nahas, Nms Gawish, M Tarshoby, O State, Ajm Boulton, C Bijoy, B Feba, R Vilkas, C Dhaandapani, K Geetha, A Vikayakumar, D Goodridge, E Trepman, J Embil, V Viswanathan, R Shobhana, C Snehalatha, R Seena, A Ramachandran, O Desalu, F Salawu, A Jimoh, A Adekoya, O Busari, A Olokoba   +47 more
openalex   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source