Results 91 to 100 of about 191,416 (239)

Integration of IPC/WASH critical conditions into quality of care and quality improvement tools and processes: Bangladesh case study

Antimicrobial Resistance and Infection Control
Unsafe patient care in hospitals, especially in low- and middle-income countries, is often caused by poor infection prevention and control (IPC) practices; insufficient support for water, sanitation, and hygiene (WASH); and inadequate waste management ...
Martha Embrey, Shahnaz Parveen, Tamara Hafner, Hafijul Islam, Abu Zahid, Mohan P. Joshi   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Medicines management at home during the COVID-19 pandemic: a qualitative study exploring the UK patient/carer perspective. [PDF]

Int J Pharm Pract, 2021
Garfield S, Wheeler C, Boucher C, Etkind M, Lloyd J, Norton J, Ogunleye D, Taylor A, Williams M, Grimes T, Kelly D, Franklin BD.   +11 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Needs Assessment of Safe Medicines Management for Older People With Cognitive Disorders in Home Care: An Integrative Systematic Review. [PDF]

Front Neurol, 2021
Vaismoradi M, Behboudi-Gandevani S, Lorenzl S, Weck C, Paal P.   +4 more
europepmc   +1 more source

Machine learning-based risk prediction model for medication administration errors in neonatal intensive care units: A prospective direct observational study

Digital Health
Objective Neonates’ physiological immaturity and complex dosing requirements heighten their susceptibility to medication administration errors (MAEs), with the potential for severe harm and substantial economic impact on healthcare systems. Developing an
Josephine Henry Basil, Wern Han Lim, Sharifah M. Syed Ahmad, Chandini Menon Premakumar, Nurul Ain Mohd Tahir, Adliah Mhd Ali, Zamtira Seman, Shareena Ishak, Noraida Mohamed Shah   +8 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Investigating the challenges and opportunities for medicines management in an NHS field hospital during the COVID-19 pandemic. [PDF]

Eur J Hosp Pharm, 2021
de Val J, Sohal G, Sarwar A, Ahmed H, Singh I, Coleman JJ.   +5 more
europepmc   +1 more source

Quality of adverse drug reaction reports submitted to the national pharmacovigilance center of Nepal: a pre- and post-training evaluation

BMC Medical Education
Background Pharmacovigilance (PV) plays a critical role in monitoring and evaluating adverse drug reactions (ADRs) to ensure the safety of marketed medical products.
Sushil Nepal, Shyam Shah, Narayan Prasad Dhakal, Umanga Tripathee, Santusta Adhikari, Sunil Shrestha, Birna Trap, Tamara Hafner, Andy Stergachis   +8 more
doaj   +1 more source