Results 101 to 110 of about 3,704,269 (327)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Distributed medium access control protocol based on successive collision detection for dense wireless sensor networks

open access: yesInternational Journal of Distributed Sensor Networks, 2016
The medium access control protocol plays an important role to decrease access collisions in dense wireless sensor networks where multiple sensors in the same vicinity attempt to transmit a packet simultaneously.
Hyun-Ho Choi   +4 more
doaj   +1 more source

A cross layer multi hop network architecture for wireless Ad Hoc networks [PDF]

open access: yes, 2011
In this paper, a novel decentralized cross-layer multi-hop cooperative network architecture is presented. Our architecture involves the design of a simple yet efficient cooperative flooding scheme,two decentralized opportunistic cooperative forwarding ...
Erkip, Elza   +4 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

C-DAM: CONTENTION BASED DISTRIBUTED RESERVATION PROTOCOL ALLOCATION ALGORITHM FOR WIMEDIA MEDIUM ACCESS CONTROL [PDF]

open access: yesJournal of Engineering Science and Technology, 2017
WiMedia Medium Access Control (MAC) provides high rate data transfer for wireless networking thereby enables construction of high speed home networks.
UMADEVI K. S., ARUNKUMAR THANGAVELU
doaj  

Dynamical Spectrum Sharing and Medium Access Control for Heterogeneous Cognitive Radio Networks

open access: yesInternational Journal of Distributed Sensor Networks, 2016
This paper tackles the issue of spectrum sharing and medium access control among heterogeneous secondary users. Two solutions are proposed in this paper.
Ahmed Mohamedou   +3 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

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