Results 131 to 140 of about 31,068 (231)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Analyzing split channel medium access control schemes,” [PDF]
, 2005 : In order to improve the throughput performance of Medium Access Control (MAC) schemes in wireless communication networks, some researchers proposed to divide a single shared channel into several subchannels: one as control sub-channel and the others as
Jing Deng +5 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Energy-efficient medium access control in wireless sensor networks [PDF]
, 2009 Medium access control for wireless sensor networks has been an activeresearch area in the past decade. This chapter discusses a set of important medium access control (MAC) attributes and possible design trade-offs in protocol design, with an emphasis on
Robin Ram Mohan Doss (13090617) +1 more
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A survey of medium access control protocols for wireless ad hoc networks
Semina: Ciências Exatas e Tecnológicas, 2004 A number of issues distinguishes Medium Access Control (MAC) protocols for wireless networks from those used in wireline systems. In addition, for ad-hoc networks, the characteristics of the radio channel, the diverse physical-layer technologies ...
Elvio João Leonardo +1 more
doaj
Medium Access Control in Wireless Sensor Networks [PDF]
, 2003 This paper reviews medium access control (MAC), an enabling technology in wireless sensor networks. MAC protocols control how sensors access a shared radio channel to communicate with neighbors.
Wei Ye, John Heidemann
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source