Results 251 to 260 of about 230,318 (346)

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

open access: yesAnnals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi   +10 more
wiley   +1 more source

Topographical Variation of Iron‐Rimmed Lesions in the Multiple Sclerosis Brain and Spinal Cord: A Neuropathological Study

open access: yesAnnals of Neurology, EarlyView.
Paramagnetic‐rim lesions are a novel diagnostic marker in multiple sclerosis (MS) and are associated with poor prognosis due to their link with chronic inflammation and disease progression. Analyzing 46 postmortem MS cases, researchers found no iron rims in 67 white matter and 85 grey matter spinal cord lesions, despite most being active.
Marco Pisa   +10 more
wiley   +1 more source

Features of Peripheral T Cell Remigration into the Thymus. [PDF]

open access: yesInt J Mol Sci
Kalinina AA, Khromykh LM, Kazansky DB.
europepmc   +1 more source

Myelitis‐Predominant Aggressive Phenotype: Unveiling Unique Patterns of Late‐Onset Neuromyelitis Optica Spectrum Disorders

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to compare clinical features and prognosis of late‐onset neuromyelitis optica spectrum disorder (LO‐NMOSD, onset age ≥60 years) with adult‐onset NMOSD (AO‐NMOSD, onset age 18–59 years), and to provide insights for individualized management in elderly patients.
Ya‐Lan Pu   +15 more
wiley   +1 more source

Recurrent pediatric posterior fossa anaplastic ependymoma managed with multiple resections: illustrative case. [PDF]

open access: yesJ Neurosurg Case Lessons
Kumabe T   +7 more
europepmc   +1 more source

Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt

open access: yesAnnals of Neurology, EarlyView.
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez   +5 more
wiley   +1 more source

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