Results 171 to 180 of about 30,038 (274)

Use of the IlluminOss Photodynamic Bone Stabilisation System Following Stereotactic Body Radiation Therapy for Limb‐Sparing in Six Dogs With Presumptive Appendicular Osteosarcoma

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Osteosarcoma is the most common primary bone tumour in dogs, with approximately 75% of cases occurring in the appendicular skeleton. Standard‐of‐care therapy consists of limb amputation followed by carboplatin chemotherapy. A minority of dogs have limb‐sparing treatments including stereotactic body radiation therapy (SBRT) or surgery. SBRT has
Emily A. Pope   +6 more
wiley   +1 more source

CT‐Based Radiomic Features Predict Cervical Lymph Node Metastasis in Dogs With Oral Malignancy: A Machine Learning Study Using Leave‐One‐Patient‐Out Cross‐Validation

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Accurate preoperative identification of cervical lymph node (LN) metastasis is essential for staging and treatment planning in dogs with oral malignancy, yet conventional imaging offers limited diagnostic sensitivity. This retrospective study evaluated whether CT‐derived radiomic features, combined with machine learning classifiers, could ...
Christopher J. Pinard   +5 more
wiley   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Presumptive Acute Post‐Hypoxic Myoclonus Following Return of Spontaneous Circulation in a Cat and a Dog

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To describe the clinical presentation of presumptive acute post‐hypoxic myoclonus in a cat and a dog after cardiopulmonary arrest (CPA). In people, acute post‐hypoxic myoclonus is a transient focal, multifocal, or generalized rhythmic myoclonus that results from global hypoxic–ischemic brain injury and may be cortical or subcortical ...
Theofanis Liatis   +2 more
wiley   +1 more source

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

open access: yesExperimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal   +9 more
wiley   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

open access: yesExperimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths   +3 more
wiley   +1 more source

Breathing irregularities and postnatal hypoxaemia in an experimental model of essential hypertension

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Neonatal spontaneously hypertensive rats (SHRs) exhibit inherent respiratory dysfunction in early life, including oscillatory breathing patterns and apnoeic events that cause oxygen desaturation and brain hypoxia, in addition to an impaired hypoxic ventilatory response.
Beatriz N. Vieira   +7 more
wiley   +1 more source

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1588-1601, 1 October 2026.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley   +8 more
wiley   +1 more source

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