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Current Opinion in Neurology, 1999
The utilization of multi-modal therapy in the treatment of medulloblastoma has improved survival rates and overall outcome. Recent large clinical trials have supported the use of radiation and chemotherapy as adjuvant treatment. Treatment advances have been made despite a poor understanding of the biological underpinnings of medulloblastoma.
A T, Reddy, R J, Packer
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The utilization of multi-modal therapy in the treatment of medulloblastoma has improved survival rates and overall outcome. Recent large clinical trials have supported the use of radiation and chemotherapy as adjuvant treatment. Treatment advances have been made despite a poor understanding of the biological underpinnings of medulloblastoma.
A T, Reddy, R J, Packer
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Journal of Child Neurology, 2009
Medulloblastoma is the most common malignant brain tumor in children. Patients with medulloblastoma are stratified into ‘‘standard’’ and ‘‘high’’ risk categories based on age at diagnosis, degree of surgical resection, and disease spread. In children older than 3 years of age, the long-term survival can be achieved in approximately 85% of standard ...
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Medulloblastoma is the most common malignant brain tumor in children. Patients with medulloblastoma are stratified into ‘‘standard’’ and ‘‘high’’ risk categories based on age at diagnosis, degree of surgical resection, and disease spread. In children older than 3 years of age, the long-term survival can be achieved in approximately 85% of standard ...
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Current Treatment Options in Neurology, 2003
Medulloblastomas, primitive neuroectodermal tumors of the cerebellum, comprise 20% of all pediatric brain tumors and are the most common solid neoplasm in children. Primitive neuroectodermal tumors are believed to arise from cerebellar granule cell precursors.
Catherine A., Mazzola, Ian F., Pollack
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Medulloblastomas, primitive neuroectodermal tumors of the cerebellum, comprise 20% of all pediatric brain tumors and are the most common solid neoplasm in children. Primitive neuroectodermal tumors are believed to arise from cerebellar granule cell precursors.
Catherine A., Mazzola, Ian F., Pollack
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Critical Reviews in Oncology/Hematology, 2011
Among all the childhood central nervous system tumours, medulloblastoma and other neuroectodermal tumours account for 16-25% of cases. The causative factors of medulloblastoma/PNET have not been well established. It is more frequent in boys than in girl and in children than in adults.
Maura Massimino +7 more
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Among all the childhood central nervous system tumours, medulloblastoma and other neuroectodermal tumours account for 16-25% of cases. The causative factors of medulloblastoma/PNET have not been well established. It is more frequent in boys than in girl and in children than in adults.
Maura Massimino +7 more
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No shinkei geka. Neurological surgery, 2022
Current treatment protocols for medulloblastomas(MBs)stratify patients into high and average risk groups according to their age, metastatic status, and residual tumor volume after resection. Recent genetic and molecular biological reserach revealed that MBs are classified into at least four core subgroups - WNT, SHH, Group 3, and Group 4 - based on ...
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Current treatment protocols for medulloblastomas(MBs)stratify patients into high and average risk groups according to their age, metastatic status, and residual tumor volume after resection. Recent genetic and molecular biological reserach revealed that MBs are classified into at least four core subgroups - WNT, SHH, Group 3, and Group 4 - based on ...
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Journal of Neuro-Oncology, 1993
A 9-day-old female presented with a large infra- and supratentorial medulloblastoma was treated by surgery, irradiation and chemotherapy. The infant suffered from vomit a few days after birth. She was hospitalized shortly thereafter, when head enlargement was noted. A CT scan taken on admission disclosed a large mass lesion in the cerebellum, extending
T, Kayama +3 more
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A 9-day-old female presented with a large infra- and supratentorial medulloblastoma was treated by surgery, irradiation and chemotherapy. The infant suffered from vomit a few days after birth. She was hospitalized shortly thereafter, when head enlargement was noted. A CT scan taken on admission disclosed a large mass lesion in the cerebellum, extending
T, Kayama +3 more
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Neuroradiology, 1989
In children medulloblastoma is a commonly encountered posterior fossa midline tumour in which cystic degeneration is not uncommon. A cystic medulloblastoma without solid component has, however, not been described. We report a 12-year-old boy with a posterior fossa midline cystic lesion on CT with surgical and histological confirmation of the diagnosis.
A K, Mahapatra, H K, Paul, C, Sarkar
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In children medulloblastoma is a commonly encountered posterior fossa midline tumour in which cystic degeneration is not uncommon. A cystic medulloblastoma without solid component has, however, not been described. We report a 12-year-old boy with a posterior fossa midline cystic lesion on CT with surgical and histological confirmation of the diagnosis.
A K, Mahapatra, H K, Paul, C, Sarkar
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JAAPA, 2017
ABSTRACT Brain tumors are the most common solid tumor malignancies in childhood, and among them, medulloblastoma occurs with the greatest frequency. Because medulloblastomas occur in the posterior fossa, the presenting symptoms often are vague complaints and diagnosis may be delayed.
Alyssa, Quinlan, Denise, Rizzolo
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ABSTRACT Brain tumors are the most common solid tumor malignancies in childhood, and among them, medulloblastoma occurs with the greatest frequency. Because medulloblastomas occur in the posterior fossa, the presenting symptoms often are vague complaints and diagnosis may be delayed.
Alyssa, Quinlan, Denise, Rizzolo
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Tumori Journal, 1970
Desmoplastic medulloblastoma is a variety of the typical cerebellar tumor, characterized by distinctive clinical and morphological features. It usually occurs in adults, is localized in a lateral lobe and shows expansive rather than infiltrative patterns of growth with early leptomeningeal involvement.
L, Pollice, F, Marzullo
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Desmoplastic medulloblastoma is a variety of the typical cerebellar tumor, characterized by distinctive clinical and morphological features. It usually occurs in adults, is localized in a lateral lobe and shows expansive rather than infiltrative patterns of growth with early leptomeningeal involvement.
L, Pollice, F, Marzullo
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Acta Neurochirurgica, 1979
51 medulloblastomas under 12 years of age were treated from 1966 through 1977. 50 patients underwent craniotomy and 39 of them completed postoperative radiation therapy. Surgical mortality rate of primary posterior fossa craniotomy was 8%. One year survival rate was 71.4%, 3 years 45.6% and 5 years 34.5%.
A J, Raimondi, T, Tomita
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51 medulloblastomas under 12 years of age were treated from 1966 through 1977. 50 patients underwent craniotomy and 39 of them completed postoperative radiation therapy. Surgical mortality rate of primary posterior fossa craniotomy was 8%. One year survival rate was 71.4%, 3 years 45.6% and 5 years 34.5%.
A J, Raimondi, T, Tomita
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