Results 1 to 10 of about 3,256 (162)

NK Cell Phenotype Is Associated With Response and Resistance to Daratumumab in Relapsed/Refractory Multiple Myeloma. [PDF]

Hemasphere, 2023
The CD38‐targeting antibody daratumumab has marked activity in multiple myeloma (MM). Natural killer (NK) cells play an important role during daratumumab therapy by mediating antibody‐dependent cellular cytotoxicity via their FcγRIII receptor (CD16), but they are also rapidly decreased following initiation of daratumumab treatment. We characterized the
Verkleij CPM, Frerichs KA, Broekmans MEC, Duetz C, O'Neill CA, Bruins WSC, Homan-Weert PM, Minnema MC, Levin MD, Broijl A, Bos GMJ, Kersten MJ, Klein SK, Shikhagaie MM, Casneuf T, Abraham Y, Smets T, Vanhoof G, Cortes-Selva D, van Steenbergen L, Ramos E, Verona RI, Krevvata M, Sonneveld P, Zweegman S, Mutis T, van de Donk NWCJ.   +26 more
europepmc   +2 more sources

Sentimental Analysis of Twitter Users from Turkish Content with Natural Language Processing. [PDF]

Comput Intell Neurosci, 2022
Artificial Intelligence has guided technological progress in recent years; it has shown significant development with increased academic studies on Machine Learning and the high demand for this field in the sector. In addition to the advancement of technology day by day, the pandemic, which has become a part of our lives since early 2020, has led to ...
Balli C, Guzel MS, Bostanci E, Mishra A.
europepmc   +2 more sources

Monocyte-mediated metabolic rewiring via CD31-CD38 interactions promotes growth and drug-resistance in multiple myeloma. [PDF]

Hemasphere
Abstract Multiple myeloma (MM) cells interact with different components of the bone marrow (BM) microenvironment, which plays a critical role in MM progression and confers resistance to therapy. Here, we report that monocytes actively control MM cell metabolism by transferring mitochondria to MM cells, thereby increasing their mitochondrial content ...
Raoof R, Dal Collo G, Simon-Molas H, Tzortzi P, Kulaj K, Demirez EN, Massaro C, Poels R, Korst CLBM, O'Neill CA, Bruins WSC, Broekmans MEC, Behradkia P, Krevvata M, Zweegman S, Kater AP, Baglio SR, Mutis T, van de Donk NWCJ.   +18 more
europepmc   +2 more sources

Effect of Modular Training on Self-Management, Disease, and Treatment Adaptation in Individuals With Hypertension: A Randomized Controlled Trial. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT Hypertension requires sustained self‐management, behavioral adaptation, and effective patient education. Individuals often experience insufficient knowledge, low motivation, and difficulty maintaining treatment behaviors. This randomized controlled trial evaluated the effect of nurse‐led modular education on self‐efficacy, medication adherence,
Keşer E, Atik D, Özcan Yüce U.
europepmc   +2 more sources

Leukocyte infiltration patterns and structural changes in severe asthmatics with variable degree of clinical control [PDF]

Clin Transl Allergy, 2015
Clinical and Translational Allergy, Volume 5, Issue S2, 23 March 2015.
Anders B, Andersson C, Hoffmann H, Mori M, Shikhagaie M, Krohn I, Dahl R, Bjermer L, Erjefält J.   +8 more
europepmc   +2 more sources

Behaviour of passage time for a queueing network model with feedback: a simulation study

International Journal of Mathematics and Mathematical Sciences, Volume 2004, Issue 24, Page 1267-1278, 2004., 2004
The study of the queueing system presented in this note was motivated by its possible application to a multiprogramming computer system. The paper considers a closed network with two service centres with feedback. The steady‐state behaviour of the passage time, the random times for a job to traverse a portion of the network, is examined through ...
Bidyut K. Medya
wiley   +2 more sources

Management of venous thromboembolism in patients with advanced gastrointestinal cancers: what is the role of novel oral anticoagulants? [PDF]

Thrombosis, 2012
Venous thromboembolism (VTE) is a frequent complication of gastrointestinal cancers that increases morbidity and may impact mortality. Low‐molecular‐weight heparins (LMWHs) and vitamin K antagonists (VKAs) are standard anticoagulation options for the ambulatory gastrointestinal cancer patient with VTE, but both of these agents are challenging to use ...
Martin LK, Bekaii-Saab T.
europepmc   +2 more sources

Medya ve Toplum

Selçuk Üniversitesi Sosyal Bilimler Meslek Yüksekokulu Dergisi, 2019
Medya olgusu ortaya çıktığı dönemden günümüze kadar insanlar ve toplum üzerinde etkili olmuştur. Bu etkinin boyutu medyanın ulaşılabilirlik seviyesi ile doğru orantılı olarak değişmiştir. İlk dönemlerde yalnızca yazılı şekilde gerçekleşen medya faaliyetleri oldukça az insan üzerinde etkili olurken zaman içinde sesli ve görsel medya yapılarının oluşması
Pelin VARDARLIER, Cem ZAFER
openaire   +5 more sources

Earnings Call Scripts Generation With Large Language Models Using Few‐Shot Learning Prompt Engineering and Fine‐Tuning Methods

Applied AI Letters, Volume 6, Issue 1, February 2025.
ABSTRACT Company earnings calls are pivotal events that offer crucial insights into a company's financial well‐being and future outlook. Large language models (LLMs) present a promising avenue for automatically generating the initial draft of earnings call scripts, leveraging financial data and past examples.
Sovik Kumar Nath, Yanyan Zhang, Jia Vivian Li   +2 more
wiley   +1 more source

Women's Dharma: Parwati Soepangat and Buddhist Feminist Theology in Postcolonial Indonesia*

Journal of Religious History, Volume 48, Issue 4, Page 423-441, December 2024.
This article uses the life and career of Parwati Soepangat as a case study to shed light on the narrative of Buddhist women in postcolonial Indonesia. It contends that, unlike Theravāda Buddhist‐majority nations in mainland Southeast Asia, Indonesia's lack of a patriarchal monastic authority allowed Buddhist women, like Parwati Soepangat, to emerge ...
Jack Meng‐Tat Chia
wiley   +1 more source