Results 61 to 70 of about 7,372,781 (263)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

A Lifecycle‐Aware Optimization Framework for Low‐Carbon Material Selection in Engineering Product Design

Engineering Reports
Achieving carbon neutrality in engineering design requires effective emission reduction strategies throughout the entire product lifecycle. Material selection is a key element in this process, as it spans multiple stages and has a decisive impact on ...
Fuqiang Xue, Feng Xue
doaj   +1 more source

Consumption and Standard of Living [PDF]

Annals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics, 2016
Living standards are an indicator mainly economic which can be defined as quantitative aspect of meeting the economic needs of an individual or a community and aims the way how the activity of material and nonmaterial production relates and contributes ...
Cecilia Elena VADUVA
doaj  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Groups with volunteers cardiac surgery patients: experience in a cardiovascular rehabilitation department

Monaldi Archives for Chest Disease, 2015
Objectives: This article aimed to describe a new experience activated inside of a more general psychological approach for patients who underwent cardiac surgery intervention.
Benedetta Basagni, Luana Pancani, Valerio Brambilla, Paolo Coruzzi   +3 more
doaj   +1 more source

Plasma enhanced atomic layer deposition of TiO2 thin films for photocatalytic application

, 2009
1
맹완주, 김형준, Du-Hwan Jo, 손종역, 이창수, Jungwon Kim, Wonyong Choi   +6 more
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Relations between selected social characteristics and meeting basic human needs

Revija za Geografijo, 2018
The composition provides findings on the importance of the place of residence and the selected socioeconomic characteristics in meeting basic human needs and represents the role of the place of residence, age, material situation and lifestyle in the ...
Maja Hadner
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source