Results 1 to 10 of about 20,938 (229)

The position of mefloquine as a 21^st century malaria chemoprophylaxis [PDF]

Malaria Journal, 2010
Background Malaria chemoprophylaxis prevents the occurrence of the symptoms of malaria. Travellers to high-risk Plasmodium falciparum endemic areas need an effective chemoprophylaxis.
Regep Loredana, Adamcova Miriam, Schlagenhauf Patricia, Schaerer Martin T, Rhein Hans-Georg   +4 more
doaj   +2 more sources

Mefloquine resistant malaria in cameroon and correlation with resistance quinine [PDF]

Memorias do Instituto Oswaldo Cruz, 1992
Based on the results of in vitro sensitivity of Plasmodium falciparum to chloroquine, quinine and mefloquine, and evaluation of drug consumption conducted in 1987-1988 in four areas in the noth and south-west of Cameron, two opposite situations were ...
P. Brasseur, J. Kouamouo, R. S. Moyou, P. Druilhe   +3 more
doaj   +2 more sources

Adverse effects of the antimalaria drug, mefloquine: due to primary liver damage with secondary thyroid involvement? [PDF]

BMC Public Health, 2002
Background Mefloquine is a clinically important antimalaria drug, which is often not well tolerated. We critically reviewed 516 published case reports of mefloquine adverse effects, to clarify the phenomenology of the harms associated with mefloquine ...
Herxheimer Andrew, Croft Ashley M
doaj   +4 more sources

A high performance liquid chromatographic assay of Mefloquine in saliva after a single oral dose in healthy adult Africans [PDF]

Malaria Journal, 2012
Background Mefloquine-artesunate is a formulation of artemisinin based combination therapy (ACT) recommended by the World Health Organization and historically the first ACT used clinically.
Gbotosho Grace O, Happi Christian T, Lawal Omowunmi, Sijuade Abayomi, Sowunmi Akin, Oduola Ayoade   +5 more
doaj   +4 more sources

Use of mefloquine in children - a review of dosage, pharmacokinetics and tolerability data [PDF]

Malaria Journal, 2011
Background Use of anti-malarial medication in children is hampered by a paucity of dosage, pharmacokinetic and tolerability data. Methods Data on the use of mefloquine in children, particularly in young children weighing less than 20 kg, were reviewed ...
Schaerer Martin T, Regep Loredana, Adamcova Miriam, Schlagenhauf Patricia, Bansod Sudhir, Rhein Hans-Georg   +5 more
doaj   +3 more sources

Structural basis of PANX1 permeation and positive modulation by mefloquine. [PDF]

Nat Commun
Li Y, Ruan Z, Lee J, Orozco IJ, Zhou E, Du J, Lü W.   +6 more
europepmc   +2 more sources

Innovative application of mefloquine and Methacycline in combating Tet(X3/X4)-positive Escherichia coli infections. [PDF]

BMC Microbiol
Zhou Q, Xue J, Li J, Liu Z, Zou Y, Dai R, Gu K, Zhou Y.   +7 more
europepmc   +3 more sources

A common DNA deletion altering the 3'UTR of mdr1 is associated with reduced mefloquine susceptibility in P. vivax parasites from Cambodian patients. [PDF]

Nat Commun
Ko K, Tebben K, Andrianinarivomanana T, Orban A, Grünebast J, Eng V, Eam R, Khim N, Feufack-Donfack LB, Salvador J, Sa JM, Wellems TE, Lek D, Popovici J, Serre D.   +14 more
europepmc   +3 more sources

Prediction of improved antimalarial chemotherapy of artesunate-mefloquine in combination with mefloquine sensitive and resistant Plasmodium falciparum malaria.

PLoS ONE, 2023
BackgroundDeclining in susceptibility of Plasmodium falciparum to mefloquine is reported in South-East Asia. A revisiting on mefloquine pharmacokinetics-pharmacodynamics (PK/PD) could assist in finding new appropriate dosage regimens in combination with ...
Teerachat Saeheng, Kesara Na-Bangchang
doaj   +2 more sources

Mefloquine Blockade of Pannexin1 Currents: Resolution of a Conflict [PDF]

Cell Communication and Adhesion, 2010
David C Spray, Eliana Scemes
exaly   +2 more sources