Results 91 to 100 of about 20,957 (246)

In Vivo and In Vitro Taste Assessment of Artesunate-Mefloquine, Praziquantel, and Benznidazole Drugs for Neglected Tropical Diseases and Pediatric Patients

, 2021
Janine Boniatti, Marcelo R. R. Tappin, Rafaela Teixeira, Tamires de A V Gandos, Luis P. S. Rios, Izabelle A. M. Ferreira, Karina C. Oliveira, Sabrińa Calil-Eliás, Aíla Karla Mota Santana, Laís Bastos da Fonseca, Flávio M. Shimizu, Olívia Carr, Osvaldo N. Oliveira, Fábio Moysés Lins Dantas, Fábio Coelho Amendoeira, Alessandra Lifsitch Viçosa   +15 more
openalex   +1 more source

Rational Risk-Benefit Decision-Making in the Setting of Military Mefloquine Policy

Journal of Parasitology Research, 2015
Mefloquine is an antimalarial drug that has been commonly used in military settings since its development by the US military in the late 1980s. Owing to the drug’s neuropsychiatric contraindications and its high rate of inducing neuropsychiatric symptoms,
Remington L. Nevin
doaj   +1 more source

Activity of mefloquine and mefloquine derivatives against Echinococcus multilocularis

International Journal for Parasitology: Drugs and Drug Resistance, 2018
The cestode E. multilocularis causes the disease alveolar echinococcosis (AE) in humans. The continuously proliferating metacestode (larval stage) of the parasite infects mostly the liver and exhibits tumor-like growth.
Reto Rufener, Dominic Ritler, Jana Zielinski, Luca Dick, Emerson Teixeira da Silva, Adriele da Silva Araujo, Deborah Elisabeth Joekel, David Czock, Christine Goepfert, Adriana Marques Moraes, Marcus Vinicius Nora de Souza, Joachim Müller, Meike Mevissen, Andrew Hemphill, Britta Lundström-Stadelmann   +14 more
doaj   +1 more source

Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro [PDF]

, 2017
Objectives Mefloquine has interesting antischistosomal properties, hence it might be an attractive partner drug for combination treatment with praziquantel.
Keiser, Jennifer, Manneck, Theresia, Vargas, Mireille   +2 more
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Prospective evaluation of BDProbeTec strand displacement amplification (SDA) system for diagnosis of tuberculosis in non-respiratory and respiratory samples. [PDF]

, 2004
Nucleic acid amplification techniques (NAATs) have been demonstrated to make significant improvements in the diagnosis of tuberculosis (TB), particularly in the time to diagnosis and the diagnosis of smear-negative TB. The BD ProbeTec strand displacement
Billington, OJ, Gillespie, SH, Gosling, RD, Ling, CL, Lipman, MC, McHugh, TD, Patel, S, Pope, CF   +7 more
core   +2 more sources

Malaria Prevention, Mefloquine Neurotoxicity, Neuropsychiatric Illness, and Risk-Benefit Analysis in the Australian Defence Force

Journal of Parasitology Research, 2015
The Australian Defence Force (ADF) has used mefloquine for malaria chemoprophylaxis since 1990. Mefloquine has been found to be a plausible cause of a chronic central nervous system toxicity syndrome and a confounding factor in the diagnosis of existing ...
Stuart McCarthy
doaj   +1 more source

The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria

Malaria Journal, 2009
Background Mefloquine and artesunate combination therapy is the recommended first-line treatment for uncomplicated malaria throughout much of south-east Asia. Concerns have been raised about the potential central nervous system (CNS) effects of both drug
Singhasivanon Pratap, Viladpainguen Jacher, Thwai Kyaw, Hla Eh, Arunjerdja Ratree, Dubowitz Lilly M, Ambler Michael T, Luxemburger Christine, Nosten François, McGready Rose   +9 more
doaj   +1 more source

In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates.

, 2014
A sequence of computational methods was used for predicting novel drug targets against drug resistant malaria parasite Plasmodium falciparum. Comparative genomics, orthologous protein analysis among same and other malaria parasites and protein-protein ...
Altschul, Andrews, Anishetty, Arama, Berman, Bernstein, Bhasin, Boeckmann, Chang, Chawley, Chen, Colovos, Corpet, David Charles Warhurst, Eisenberg, Finn, Franceschini, Ghosh, Irwin, Irwin, Kanehisa, Konc, Krogh, Kushwaha, Larsen, Laskowski, Ludin, Miller, Morris, Mrutyunjay Suar, Mulder, Pieper, Pierleoni, Pontius, Rajani Kanta Mahapatra, Sali, Subhashree Rout, Sun, Tam, von Mering, Wallner, Wiederstein, World Health Organization, Yang, Yeh, Zhexin   +45 more
core   +1 more source

Compliance with a three-day course of artesunate-mefloquine combination and baseline anti-malarial treatment in an area of Thailand with highly multidrug resistant falciparum malaria

Malaria Journal, 2010
Background Artemisinin-based combination therapy (ACT) is presently recommended by the World Health Organization as first-line treatment for uncomplicated Plasmodium falciparum malaria in several countries, as a mean of prolonging the effectiveness of ...
Na-Bangchang Kesara, Banmairuroi Vick, Bualombai Pongwit, Congpuong Kanungnit   +3 more
doaj   +1 more source

Production and characterization of different types of malaria pigment (hemozoin) and their potential use for screening for hemozoin inhibiting drugs [PDF]

, 2012
Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2012Malarial pigment, hemozoin, appears to modulate the immune system, however it remains controversial if it has stimulatory or inhibitory effects ...
Góis, Ana Margarida Ferreira, 1988-
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