Results 21 to 30 of about 20,957 (246)

Molecular evidence of incipient speciation within Anopheles gambiae s.s. in West Africa [PDF]

open access: yes, 2001
We karyotyped and identified by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) analysis Anopheles gambiae s.s. samples collected in several African countries. The data show the existence of two non-panmictic molecular forms,
Akogbeto, M   +6 more
core   +1 more source

Progressive multifocal leukoencephalopathy successfully treated with mefloquine and literature review [PDF]

open access: yesEncephalitis, 2021
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection due to reactivation of John Cunningham virus (JCV). The diagnosis depends on evidence from clinical, imaging, and virologic studies.
Sungjoon Yoon   +3 more
doaj   +1 more source

Cost-effectiveness analysis of malaria chemoprophylaxis for travellers to West-Africa [PDF]

open access: yes, 2010
Background: The importation of malaria to non-endemic countries remains a major cause of travel-related morbidity and a leading cause of travel-related hospitalizations. Currently they are three priority medications for malaria prophylaxis to West Africa:
Widmer, Lukas L   +4 more
core   +3 more sources

Patient age does not affect mefloquine concentrations in erythrocytes and plasma during the acute phase of falciparum malaria

open access: yesBrazilian Journal of Infectious Diseases, 2016
Objective: To evaluate whether patient age has a significant impact on mefloquine concentrations in the plasma and erythrocytes over the course of treatment for uncomplicated falciparum malaria. Methods: A total of 20 children aged between 8 and 11 years
José Luiz Fernandes Vieira   +4 more
doaj   +1 more source

Malaria in Nonimmune Travelers [PDF]

open access: yes, 1994
Background: With the current increase of international travel to tropical endemic areas, the incidence of malaria being imported into nonendemic countries has increased significantly.
Jelinek, Thomas   +2 more
core   +1 more source

Pharmacokinetic Profile of Oral Administration of Mefloquine to Clinically Normal Cats: A Preliminary In-Vivo Study of a Potential Treatment for Feline Infectious Peritonitis (FIP)

open access: yesAnimals, 2020
The pharmacokinetic profile of mefloquine was investigated as a preliminary study towards a potential treatment for feline coronavirus infections (such as feline infectious peritonitis) or feline calicivirus infections.
Jane Yu   +3 more
doaj   +1 more source

Mefloquine, a Potent Anti-severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Drug as an Entry Inhibitor in vitro

open access: yesFrontiers in Microbiology, 2021
Coronavirus disease 2019 (COVID-19) has caused serious public health, social, and economic damage worldwide and effective drugs that prevent or cure COVID-19 are urgently needed.
Kaho Shionoya   +33 more
doaj   +1 more source

Exploration of in Vivo Efficacy of Artemether-Lumefantrine Against Uncomplicated Plasmodium Falciparum Malaria in Under Fives in Tabora Region, Tanzania. [PDF]

open access: yes, 2013
Tanzania adopted artemether-lumefantrine (AL) as first-line drug for uncomplicated malaria in 2006. Recently, there was an anecdotal report on high malaria recurrence rate following AL treatment in in the (urban and peri-urban), western part of Tanzania.
Hulser, Ruth   +5 more
core   +3 more sources

Pharmacokinetics of mefloquine administered with artesunate in patients with uncomplicated falciparum malaria from the Brazilian Amazon basin

open access: yesMalaria Journal, 2018
Background A fixed-dose combination of mefloquine with artesunate was evaluated in cases of falciparum malaria in the Brazilian Amazon basin with acceptable efficacy, safety and tolerability.
Michelle V. D. Ferreira   +5 more
doaj   +1 more source

Pioneer Use of Antimalarial Transdermal Combination Therapy in Rodent Malaria Model

open access: yesPathogens, 2023
We have previously reported 1,2,6,7-tetraoxaspiro [7.11]nonadecane (N-89) as a promising antimalarial compound. In this study, we evaluated the effect of transdermal therapy (tdt) of N-89 in combination (tdct) with other antimalarials as an application ...
Nagwa S. M. Aly   +8 more
doaj   +1 more source

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