Results 81 to 90 of about 20,957 (246)

Evaluation of hematological changes in Plasmodium falciparum–infected patients before and after artesunate-mefloquine treatment in Dak Lak province, Vietnam [PDF]

, 2020
Quang Hong Huynh, Khanh Van Chau, Hien Thanh Pham, Hien Tinh Tran, Nhien Thuy Thanh Nguyen, Hong Duc Nguyen   +5 more
openalex   +1 more source

The Impact of pfmdr1 Gene Copy Number on the Efficacy of Dihydroartemisinin–Piperaquine in Treating Malaria in West Sumba and Kupang Districts, East Nusa Tenggara, Indonesia

Journal of Parasitology Research, Volume 2026, Issue 1, 2026.
The efficacy of antimalarial treatment, particularly artemisinin‐based combination therapy (ACT), continues to face persistent threats due to the development of drug resistance in Plasmodium falciparum. Although artemisinin derivatives remain effective, ACT regimen failure often results from decreased efficacy of the companion drug.
Irdayanti Irdayanti, Hijral Aswad, Puji B. S. Asih, Ismail E. Rozi, Herdiana Herdiana, Ajib Diptyanusa, Helen D. Prameswari, Yenni Yusuf, Bahrani Bahrani, Najdah Hidayah, I. Made Artika, Din Syafruddin, Satabdi Datta Choudhury   +12 more
wiley   +1 more source

Progress in the study of mefloquine as an antibiotic adjuvant for combination bacterial inhibition treatment

Frontiers in Cellular and Infection Microbiology
Antimicrobial resistance is among the greatest threats to public health globally, and drug repurposing strategies may be advantageous to addressing this problem.
Xiaofang Liang, Xiaofang Liang, Zhihong Liu, Zhihong Liu, Yulin Wang, Yulin Wang, Yu Zhang, Yu Zhang, Wenbo Deng, Wenbo Deng, Qianqian Liu, Zhangping Lu, Keke Li, Yanbing Chang, Lianhua Wei, Lianhua Wei   +15 more
doaj   +1 more source

The efficacy of halofantrine in the treatment of acute malaria in nonimmune travelers [PDF]

, 1992
A multicenter prospective trial was performed to investigate the efficacy and the tolerability of halofantrine in nonimmune patients with malaria imported from areas with drug-resistant falciparum parasites (mainly Africa).
Bock, H. L., Clemens, R., Fleischer, K., Kohler, B., Kretschmer, H., Löscher, Thomas, Pohle, H. D., Schlunk, T., Weinke, T.   +8 more
core   +1 more source

Malaria: 11‐Year Experience With Imported Cases at a German University Hospital and Epidemiological Trends Amid the COVID‐19 Pandemic

Journal of Parasitology Research, Volume 2026, Issue 1, 2026.
Background By the mid‐20th century, Europe eradicated endemic malaria. However, the significance of imported infections in nonendemic regions is growing. These cases often constitute the majority, can sustain transmission, trigger relapses, and increase mortality in these areas. Methods We conducted a retrospective, single‐center study of patients with
Patricia Mester, Claudia Kunst, Stephan Schmid, Katharina Zimmermann, Sigrid Bülow, Janine Rennert, Benedikt M. J. Lampl, Tobias Schilling, Martina Müller, Vlad Pavel, Satabdi Datta Choudhury   +10 more
wiley   +1 more source

Unveiling the Antimalarial Potential of Leaf Extracts of Mussaenda erythrophylla Schum. & Thonn. and Mussaenda philippica Dona Luz x M. flava in Mice

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Malaria remains a major global public health concern, particularly in tropical regions. The increasing resistance to the current antimalarial drugs highlights the urgent need for new and effective therapies. Medicinal plants offer a promising source of novel and affordable antimalarial compounds for drug development.
Prapaporn Chaniad, Arisara Phuwajaroanpong, Walaiporn Plirat, Atthaphon Konyanee, Parnpen Viriyavejakul, Abdi Wira Septama, Chuchard Punsawad, Rajib Chowdhury   +7 more
wiley   +1 more source

The management and treatment of malaria [PDF]

, 1989
Falciparum malaria can create severe complications. Antimalarial drugs such as quinine or chloroquine help in the treatment and management to these complications. The use of chemoprophylaxis is a must for persons travelling abroad to countries subject to
Gilles, Herbert M.
core  

Effect of mefloquine on biological and biochemical aspects of Lymnaea natalensis snails infected with Fasciola gigantica

Journal of Basic and Applied Zoology, 2019
Background The effect of the mefloquine drug on the survival rate, egg production, and infection of snails with Fasciola gigantica was studied. Also, the present study was designed to investigate the response of the snail Lymnaea natalensis for ...
Marwa Thabet Atwa, Fayez Ahmed Bakry
doaj   +1 more source

Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols

Malaria Journal, 2010
Background The clinical utility for mefloquine has been eroded due to its association with adverse neurological effects. Better-tolerated alternatives are required.
Melendez Victor, Lanteri Charlotte, Goodine Duane, Gerena Lucia, Gardner Sean, Cobar Jose, Caridha Diana, Bhonsle Jayendra, McCalmont William, Milner Erin, Roncal Norma, Sousa Jason, Wipf Peter, Dow Geoffrey   +13 more
doaj   +1 more source

Efficacy and Safety of Mefloquine, Artesunate, Mefloquine-Artesunate, and Praziquantel against Schistosoma haematobium: Randomized, Exploratory Open-Label Trial [PDF]

, 2017
Background. Morbidity control of schistosomiasis relies on a single drug, praziquantel. The antimalarial drug mefloquine possesses interesting antischistosomal properties, yet no clinical studies have been performed. Methods.
Adoubryn, Koffi D., Hatz, Christoph, Keiser, Jennifer, N'Goran, Eliezer K., N'Guessan, Nicaise A., Silué, Kigbafori D., Utzinger, Jürg, Vounatsou, Penelope   +7 more
core