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Mei Mei, A Daughter's Song: Review

RadioDoc Review, 2017
The most compelling aspect of Mei Mei: A Daughter’s Song is its enduring power as cultural critique. On the surface, the subject matter is the universal conflict between mother and daughter, but this radio docudrama by Taiwanese-American producer Dmae Roberts is in fact an ambitious exploration of the complex meanings of race, hybridity and cultural ...
openaire   +2 more sources

Ceftriaxone therapy attenuates brain trauma in rats by affecting glutamate transporters and neuroinflammation and not by its antibacterial effects

BMC Neuroscience, 2021
Background Ceftriaxone is a β-lactam antibiotic used to treat central nervous system infections. Whether the neuroprotective effects of ceftriaxone after TBI are mediated by attenuating neuroinflammation but not its antibacterial actions is not well ...
Sher-Wei Lim, Hui-Chen Su, Tee-Tau Eric Nyam, Chung-Ching Chio, Jinn-Rung Kuo, Che-Chuan Wang   +5 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Satisfaction in parturients receiving epidural analgesia after prenatal shared decision-making intervention: a prospective, before-and-after cohort study

BMC Pregnancy and Childbirth, 2020
Background The explanation of epidural analgesia by anesthesiologist would often begin after the parturient is admitted to the hospital. Because of labor pain, the decision of receiving epidural analgesia would often be made by the family members ...
Wan-Jung Cheng, Kuo-Chuan Hung, Chung-Han Ho, Chia-Hung Yu, Yi-Chen Chen, Ming-Ping Wu, Chin-Chen Chu, Ying-Jen Chang   +7 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Association between chronic pain and acute coronary syndrome in the older population: a nationwide population-based cohort study

BMC Geriatrics, 2023
Background Chronic pain (CP) may increase the risk of acute coronary syndrome (ACS); however, this issue in the older population remains unclear. Therefore, this study was conducted to clarify it.
Yu-Chang Liu, Chung-Han Ho, Yi-Chen Chen, Chien-Chin Hsu, Hung-Jung Lin, Chia-Ti Wang, Chien-Cheng Huang   +6 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Prunus mume genome research: current status and prospects

Ornamental Plant Research
Mei (Prunus mume) is an excellent garden tree highly praised in China, possessing both ornamental and cultural values. Breeding Mei with distinctive characteristics and high resistance has become a long-term goal to meet the visual and spiritual demands ...
Dongqing Fan, Runtian Miao, Wenjuan Lv, Zhenying Wen, Juan Meng, Xu Liu, Tangren Cheng, Qixiang Zhang, Lidan Sun   +8 more
doaj   +1 more source

Post-COVID-19 condition risk in patients with intellectual and developmental disabilities: a retrospective cohort study involving 36,308 patients

BMC Medicine, 2023
Background To date, no studies have investigated the prevalence of post-COVID-19 conditions in patients with Intellectual and Developmental Disabilities (IDD).
Ting-Hui Liu, Po-Yu Huang, Jheng-Yan Wu, Min-Hsiang Chuang, Wan-Hsuan Hsu, Ya-Wen Tsai, Pei-Hsin Kao, Chih-Cheng Lai   +7 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source