Results 131 to 140 of about 71,235 (256)

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

A phenotypic <i>in vitro</i> assay of mouse oocyte maturation identifies reversible blockers of meiotic progression for non-hormonal contraceptive discovery. [PDF]

Hum Reprod Open
Pea J, Zhu Y, Lee HC, Haky LR, Proudfoot J, Nelson R, Duncan FE.   +6 more
europepmc   +1 more source

A Real‐Life, Multicenter, Retrospective Study on Epidemiological and Clinical Features of Patients With Hidradenitis Suppurativa and Concomitant Down Syndrome

International Journal of Dermatology, EarlyView.
Summary of the clinical characteristics and 2‐year follow‐up of patients with HS and concomitant DS in a multicentre Italian cohort, highlighting earlier HS onset, clinical features, and improved disease severity, quality of life, and pain over follow‐up, supporting early screening and multidisciplinary care of this special population.
Chiara Moltrasio, Luisa Sarno, Giovanni Genovese, Federica Derlino, Dalma Malvaso, Valeria Gaspari, Marina Venturini, Federica Repetto, Gianluca Avallone, Simone Ribero, Elisa Molinelli, Oriana Simonetti, Alessandra Michelucci, Marco Romanelli, Valentina Dini, Marco Manfredini, Cristina Magnoni, Caterina Foti, Silvia Sanna, Laura Atzori, Federico Bardazzi, Riccardo Balestri, Giulia Rech, Paolo Gisondi, Raffaele Dante Caposiena Caro, Iris Zalaudek, Viviana Lora, Luca Fania, Elia Rosi, Stefano Buffon, Carlo Alberto Maronese, Alessandra Cartocci, Pietro Rubegni, Francesca Prignano, Angelo Valerio Marzano   +34 more
wiley   +1 more source

Dual roles of two Tfdps in germline nuclear meiosis and somatic nuclear fragmentation during sexual reproduction in the unicellular organism <i>Paramecium tetraurelia</i>. [PDF]

Mar Life Sci Technol
Zuo X, Wang Z, Liu M, Solberg T, Tang D, Wen Z, Wang C.   +6 more
europepmc   +1 more source

Continuous darkness is associated with improved growth performance during a high‐temperature period and sex‐specific modulation of early gonadal development in juvenile yellowtail (Seriola quinqueradiata)

Journal of Fish Biology, EarlyView.
Abstract Selective breeding of yellowtail (Seriola quinqueradiata) is expanding in Japan, increasing the demand for practical reproductive control tools in commercial aquaculture to reduce genetic risks from escapees. Slowing early gonadal development through environmental manipulation may support future sterilization strategies, particularly when ...
Yuya Hasegawa, Kiko Shibata, Taiga Abe, Takurou Hotta   +3 more
wiley   +1 more source

Specialisation of meiotic kinetochores revealed through a synthetic spindle assembly checkpoint strategy. [PDF]

Elife
Koch LB, Ghosh T, Spanos C, Marston AL.
europepmc   +1 more source

ZmMS1 coordinates ROS homeostasis, lipid allocation, and male fertility for maize breeding applications

Journal of Integrative Plant Biology, EarlyView.
The redox‐sensitive transcriptional repressor ZmMS1 coordinates reactive oxygen species homeostasis and lipid allocation for pollen exine and anther cuticle formation. Loss or precocious expression of ZmMS1 causes male sterility. Constitutive overexpression induces dwarfism and semi‐sterility. These findings enable flexible maize male‐sterility systems
Quancan Hou, Xueli An, Zhenying Dong, Biao Ma, Suowei Wu, Ke Xie, Ziwen Li, Tingwei Yan, Yilin Jiang, Taotao Zhu, Bin Ma, Lina Zhao, Yan Long, Xiangyuan Wan   +13 more
wiley   +1 more source

Chromosome-specific differences in the recombination landscape of spontaneous meiotic nondisjunction. [PDF]

Genetics
Turcotte CA, Sekelsky J.
europepmc   +1 more source

ATXR5 and ATXR6 restrict meiotic crossover formation within heterochromatin in Arabidopsis

Journal of Integrative Plant Biology, EarlyView.
The Arabidopsis H3K27 mono‐methyltransferases ATXR5 and ATXR6 repress crossovers within meiotic heterochromatin, are required for heterochromatin condensation and H3K27me1 establishment, and specifically influence the maintenance of DNA methylation in meiocytes.
Jun Zhang, Yue Yu, Han Wang, Meiling Li, Dingning Li, Chenjiang You, Yingxiang Wang, Cong Wang   +7 more
wiley   +1 more source

The Use of dN/dS Ratios to Investigate Types of Selection in Related Sexual and Asexual Lineages. [PDF]

Genome Biol Evol
Klemp FL, Hörandl E, Maraun M, Scheu S, Heimburger B.   +4 more
europepmc   +1 more source