Results 221 to 230 of about 149,546 (296)

Recurrent Chromosome Destabilization Through Repeat-Mediated Rearrangements in a Fungal Pathogen. [PDF]

Genome Biol Evol
Fouché S, Oggenfuss U, McDonald BA, Croll D.   +3 more
europepmc   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

A Precise Reproductive Calendar of Sexual and Apomictic Genotypes of <i>Eragrostis curvula</i>. [PDF]

Plants (Basel)
Selva JP, Zappacosta D, Gallo CA, Bisp P, Albertini E, Echenique V.   +5 more
europepmc   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, Volume 13, Issue 29, 22 May 2026.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Hybrid female sterility due to cohesin protection errors in mouse oocytes. [PDF]

Sci Adv
El Yakoubi W, Pan B, Akera T.
europepmc   +1 more source

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

Advanced Science, Volume 13, Issue 27, 13 May 2026.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng, Shaochen Jia, Fei Cao, Cuiping Liu, Heshuang Zhang, Gang Xu, Jixin Zhuang, Yashi Zhang, Can Liu, Yuhang Zhao, Zilin Guo, Xinjie Yuan, Jiaqing Yang, Lei Chu, Bowei Cai, Hu Zhao, Chao Yang   +16 more
wiley   +1 more source

Meiosis [PDF]

, 2019
openaire   +2 more sources

Acrylamide disrupts meiotic G2/M transition and SAC activity during oocyte maturation. [PDF]

Biol Direct
Chen S, Wang PX, Wang YT, Ke XH, Ou M, Sun SC, Liao BY, Chen X.   +7 more
europepmc   +1 more source

Age‐related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Down syndrome (DS) is the leading genetic cause of intellectual disability and Alzheimer's disease (AD), with over 90% of individuals developing AD‐related dementia (DSAD). The triplication of the APP gene on chromosome 21 drives early amyloid‐β (Aβ) accumulation, but other Hsa21 genes also contribute to pathology.
Monika Rataj Baniowska, Paige Mumford, Francesca Prestia, Pauline Stephan, Millie Beament, Marie‐Christine Birling, Chiara Lanzillotta, Letizia Ciafardini, Eugenio Barone, Gloria Lau, Claire Chevalier, Chadia Nahy, Nadia Messaddeq, Thais Lestra, Yixing Wu, Valérie Nalesso, Fabio Di Domenico, Frances Wiseman, Yann Herault   +18 more
wiley   +1 more source

MEIOC prevents continued mitotic cycling and promotes meiotic entry during mouse oogenesis. [PDF]

Development
Ushuhuda EG, Nguyen JT, Pfaltzgraff NG, Wenner SM, Kofron M, Mikedis MM.   +5 more
europepmc   +1 more source