Results 151 to 160 of about 25,464 (256)

Fenfluramine treatment and seizure‐free days in pediatric and adult patients with Lennox–Gastaut syndrome: A post hoc analysis

Epilepsia, EarlyView.
This graphical abstract provides an overview of the post hoc analysis evaluating change in percentage of seizure‐free days in pediatric and adult patients treated with fenfluramine in the Lennox‐Gastaut syndrome phase 3 study. Abstract The most common primary endpoint for assessing treatment efficacy in patients with Lennox–Gastaut syndrome (LGS) is ...
Stéphane Auvin, Ingrid E. Scheffer, Antonio Gil‐Nagel, Patrick Healy, Amélie Lothe, Mélanie Langlois, Jayne Abraham, Lieven Lagae, Kelly G. Knupp   +8 more
wiley   +1 more source

Magnetic-Assisted Fractionation of Bone Marrow Cells into Subsets Differing in CD45 Expression Levels, Surface Phenotypes and Functional Properties. [PDF]

Cells
Kandarakov OF, Polyakova NS, Belyavsky AV.   +2 more
europepmc   +1 more source

Changes in effectiveness and safety in patients with Lennox–Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open‐label extension study

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout, Orrin Devinsky, Lieven Lagae, Ingrid E. Scheffer, Renzo Guerrini, Joseph Sullivan, Antonio Gil‐Nagel, Sameer M. Zuberi, Kate Riney, Patrick Healy, Jayne Abraham, Rebecca Zhang Roper, Mélanie Langlois, Amélie Lothe, Kelly G. Knupp   +14 more
wiley   +1 more source

Fault Diagnosis of Motor Bearing Transmission System Based on Acoustic Feature Fusion. [PDF]

Sensors (Basel)
Ma L, Zhang Y, Wang Z, Niu B.
europepmc   +1 more source

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout, Joseph Sullivan, Stéphane Auvin, J. Helen Cross, Orrin Devinsky, Antonio Gil‐Nagel, Renzo Guerrini, Kelly G. Knupp, M. Scott Perry, Rocío Sánchez‐Carpintero, An‐Sofie Schoonjans, Ingrid E. Scheffer, Nicola Specchio, Adam Strzelczyk, James Wheless, Elaine C. Wirrell, Diego Morita, Patrick Healy, Mélanie Langlois, Amélie Lothe, Lieven Lagae   +20 more
wiley   +1 more source

Dual-branch hierarchical fusion network for voice-based classification of type 2 diabetes mellitus using multi-vowel acoustic features. [PDF]

Front Med Technol
Jiang P, Zhang W, Li A, Li P.
europepmc   +1 more source

Clinician Perspectives on Barriers and Enablers to Autism‐Affirming Eating Disorder Care

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Autistic people with an eating disorder (ED) report more negative experiences of ED treatment and are at greater risk of requiring higher intensity services. Current ED treatment options do not fully meet underpinning drivers of autistic people's experiences of EDs.
Emy Nimbley, Amelia Austin, Kate Tchanturia, Kai Thomas, Catherine R. G. Jones, Karri Gillespie‐Smith, Fiona Duffy   +6 more
wiley   +1 more source

Exploring the Melanoma and Pancreatic Cancer Phenotype of a Potential <i>CDKN2A</i> Founder Variant, I49T (c.146T>C; p.Ile49Thr), in Individuals of Predominantly Mexican Ancestry. [PDF]

JCO Precis Oncol
Hernandez D, Browning A, Gemmell A, Lara-Otero K, Niell-Swiller M, Mersch J, Mraz KA, Kamara D, Blanco A, Cardona Y, Chang E, Comeaux JG, Culver JO, Ford JM, Gutierrez N, Lester J, Karlan BY, Li M, Nie Q, Resendiz J, Wei ML, Ricker CN.   +21 more
europepmc   +1 more source

Turning the TIDE: Paediatric Provider Perspectives on Implementing a Transition Intervention for Eating Disorders

European Eating Disorders Review, EarlyView.
ABSTRACT Objective This qualitative study aimed to explore paediatric providers' perspectives on the acceptability, feasibility, and appropriateness of the Transition Intervention for Eating Disorders (TIDE) within existing specialised paediatric eating disorder (ED) programs to inform its refinement and implementation in real‐world clinical settings ...
Maria Nicula, Melissa Kimber, Khrista Boylan, Jennifer Couturier   +3 more
wiley   +1 more source

Zero-shot emotional speech synthesis based on feature decoupling and adaptive loss-threshold reweighting. [PDF]

PLoS One
Zhu Y, Wang Y, Zhou Y, Liu B, Zhou R.
europepmc   +1 more source