Results 31 to 40 of about 25,464 (256)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Speech reconstruction from mel frequency cepstral coefficients and pitch frequency [PDF]

2000 IEEE International Conference on Acoustics, Speech, and Signal Processing. Proceedings (Cat. No.00CH37100), 2002
This paper presents a novel low complexity, frequency domain algorithm for reconstruction of speech from the mel-frequency cepstral coefficients (MFCC), commonly used by speech recognition systems, and the pitch frequency values. The reconstruction technique is based on the sinusoidal speech representation.
Dan Chazan, Ron Hoory, Gilad Cohen, Meir Zibulski   +3 more
openaire   +2 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Footstep Recognition Using Mel Frequency Cepstral Coefficients and Artificial Neural Network

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2020
Footstep recognition is relatively new biometrics and based on the learning of footsteps signals captured from people walking on the sensing area.
Thasya Nurul Wulandari Siagian, Hilal Hudan Nuha, Rahmat Yasirandi   +2 more
doaj   +1 more source

Bearing Fault Diagnosis Based on Mel Frequency Cepstrum Coefficient and Deformable Space-Frequency Attention Network

IEEE Access, 2023
The main bearing is the core component of gas-fired generator, and its reliability directly affects the stability of the whole system. Therefore, it is of great significance to study the fault diagnosis of the main bearing of gas-fired generator.
Yunji Zhao, Nannan Zhang, Zhihao Zhang, Xiaozhuo Xu   +3 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Wavelet based feature combination for recognition of emotions

Ain Shams Engineering Journal, 2018
In this paper, authors tried to develop reduced combinational features for emotional speech recognition. The spectral/cepstral features like wavelet coefficient, LPCC (linear prediction cepstral coefficient) and MFCC (mel-frequency cepstral coefficient ...
Hemanta Kumar Palo, Mihir Narayan Mohanty   +1 more
doaj   +1 more source

Mel Frequency Cepstral Coefficient: A Review [PDF]

Proceedings of the 2nd International Conference on ICT for Digital, Smart, and Sustainable Development, ICIDSSD 2020, 27-28 February 2020, Jamia Hamdard, New Delhi, India, 2021
Shalbbya Ali, Safdar Tanweer, Syed Khalid, Naseem Rao   +3 more
openaire   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source