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Major depressive disorder with melancholia displays robust alterations in resting state heart rate and its variability: implications for future morbidity and mortality [PDF]

open access: yesFrontiers in Psychology, 2014
Background: Major depressive disorder (MDD) is associated with increased heart rate and reductions in its variability (HRV) – markers of future morbidity and mortality – yet prior studies have reported contradictory effects.
Andrew H Kemp   +2 more
exaly   +5 more sources

Catatonia and melancholia interface: exploring a new paradigm for evaluation and treatment. A case series and literature review [PDF]

open access: yesFrontiers in Psychiatry
BackgroundCatatonia has been increasingly associated with mood disorders and is recognized as a specifier in the DSM-5 and DSM-5-TR. The DSM-5-TR recognizes melancholia as a specifier for depressive episodes in major depressive disorder and bipolar ...
Yassir Mahgoub   +6 more
doaj   +3 more sources

The role of Melancholia in prostate cancer patients' depression [PDF]

open access: yesBMC Psychiatry, 2011
Background Although it is well established that prostate cancer (PCa) patients are more likely to experience clinical depression than their age-matched non-prostate cancer peers, and that such depression can have negative effects upon survival, little is
Sharpley Christopher F   +2 more
doaj   +4 more sources

Sydney Melancholia Prototype Index (SMPI): translation and cross-cultural adaptation to Brazilian Portuguese

open access: yesTrends in Psychiatry and Psychotherapy, 2020
Introduction Depression is possibly not a single syndrome but rather comprises several subtypes. DSM-5 proposes a melancholia specifier with phenotypic characteristics that could be associated with clinical progression, biological markers or therapeutic
Mateus Frizzo Messinger   +7 more
doaj   +2 more sources

Depression Severity, Slow- versus Fast-Wave Neural Activity, and Symptoms of Melancholia [PDF]

open access: yesBrain Sciences
Melancholia is a major and severe subtype of depression, with only limited data regarding its association with neurological phenomena. To extend the current understanding of how particular aspects of melancholia are correlated with brain activity ...
Christopher F. Sharpley   +5 more
doaj   +2 more sources

Exploring the legacy of Ibn Imrân’s Treatise on melancholia in contemporary psychiatry [PDF]

open access: yesEuropean Psychiatry
Introduction Melancholia is a concept deeply intertwined with the history of mood disorders in psychiatry. Isháq Ibn Imrân, a prominent Arab-Muslim physician of the 12th century, contributed significantly to the understanding of melancholia in his era ...
S. Boudriga   +6 more
doaj   +2 more sources

The Tryptophan Catabolite or Kynurenine Pathway in a Major Depressive Episode with Melancholia, Psychotic Features and Suicidal Behaviors: A Systematic Review and Meta-Analysis

open access: yesCells, 2022
Major depressive disorder (MDD) and bipolar disorder (BD) with melancholia and psychotic features and suicidal behaviors are accompanied by activated immune-inflammatory and oxidative pathways, which may stimulate indoleamine 2,3-dioxygenase (IDO), the ...
Abbas F Almulla, Hussein K Al-Hakeim
exaly   +3 more sources

Fin de l’art et la mélancolie [PDF]

open access: yesSvět Literatury, 2022
Based on the theory of Arthur Coleman Danto I try to outline possible similarities between the state of art after its end and the state of melancholy. The melancholic breaks the order, thus paradoxically drawing its boundaries.
Anna Luňáková
doaj   +1 more source

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