Results 231 to 240 of about 284,171 (356)

Direct and indirect phenotypic effects on sociability indicate potential to evolve

open access: yesJournal of Evolutionary Biology, Volume 36, Issue 1, Page 209-220, January 2023., 2023
A graphical abstract summarising the results of the article. Abstract The decision to leave or join a group is important as group size influences many aspects of organisms' lives and their fitness. This tendency to socialise with others, sociability, should be influenced by genes carried by focal individuals (direct genetic effects) and by genes in ...
David N. Fisher
wiley   +1 more source

Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging

open access: yesAging Cell, EarlyView.
Age‐related increases in IGF‐1 expression in the skin accelerate stem cell exhaustion and senescence by impairing SIRT1 function, ultimately driving hair follicle aging. Conversely, activating SIRT1, clearing senescent cells, or adopting dietary restriction can mitigate excessive IGF‐1 signaling and provide a promising strategy to rejuvenate hair ...
Yang Wang   +22 more
wiley   +1 more source

Diurnal temperature amplitude affects diamondback moth adult and next‐generation traits

open access: yesJournal of Applied Entomology, Volume 147, Issue 1, Page 63-71, February 2023., 2023
Abstract Temperature fluctuation is one of the most important factors in climate change, and research into its effects on organisms is increasing. Nonetheless, few studies have addressed its effects on insects and particularly on the parental generation.
Kun Xing, Junyu Cao, Bowen Hao, Fei Zhao
wiley   +1 more source

The Proprotein Convertase BLI‐4 Is Required for Axenic Dietary Restriction Mediated Longevity in Caenorhabditis elegans

open access: yesAging Cell, EarlyView.
In ADR‐induced longevity in C. elegans, neuronal BLI‐4 processes neuropeptides, which are then released with the assistance of UNC‐31 and GOLG‐2. ABSTRACT Dietary restriction (DR) is a well‐established method for extending lifespan across various species, including C. elegans.
Ping Wu   +3 more
wiley   +1 more source

Mutant SOD1 aggregates formed in vitro and in cultured cells are polymorphic and differ from those arising in the CNS

open access: yesJournal of Neurochemistry, Volume 164, Issue 1, Page 77-93, January 2023., 2023
In this issue Nordström et al. show that ALS associated superoxide dismutase 1 (SOD1) aggregates generated in vitro and in cell culture models are deviant from the aggregations that arise in the CNS of Tg mouse models of ALS. The study suggests that development of different strains of SOD1 aggregation in the CNS may depend on different disease ...
Ulrika Nordström   +7 more
wiley   +1 more source

Cryptic lineages and standing genetic variation across independent cane toad introductions

open access: yesMolecular Ecology, Volume 31, Issue 24, Page 6440-6456, December 2022., 2022
Abstract Widespread introduced species can be leveraged to investigate the genetic, ecological and adaptive processes underlying rapid evolution and range expansion, particularly the contributions of genetic diversity to adaptation. Rhinella marina, the cane toad, has been a focus of invasion biology for decades in Australia.
Cinnamon S. Mittan‐Moreau   +6 more
wiley   +1 more source

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