Results 251 to 260 of about 284,171 (356)

Gene model for the ortholog of <i>Roc1a</i> in <i>Drosophila eugracilis</i>. [PDF]

open access: yesMicroPubl Biol
Lawson ME   +9 more
europepmc   +1 more source

Lords of the flies: dipteran migrants are diverse, abundant and ecologically important

open access: yesBiological Reviews, EarlyView.
ABSTRACT Insect migrants are hugely abundant, with recent studies identifying the megadiverse order Diptera as the major component of many migratory assemblages. Despite this, their migratory behaviour has been widely overlooked in favour of more ‘charismatic’ migrant insects such as butterflies, dragonflies, and moths.
Will L. Hawkes   +2 more
wiley   +1 more source

Infantile Cerebellar‐Retinal Degeneration Associated With Novel ACO2 Variants: Clinical Features and Insights From a Drosophila Model

open access: yesClinical Genetics, EarlyView.
Our Translational Loop integrates patient genetic data with Drosophila models to study disease mechanisms. We identified ACO2 variants in a patient linked to ICRD and show that our animal model mirrors key aspects of the disease. These insights help pinpoint therapeutic targets, advancing research toward treatments for rare genetic disorders.
Edgar Buhl   +15 more
wiley   +1 more source

Single‐Cell Transcriptomics Uncovers Core Signature for Regulating Mitochondrial Homeostasis During Testicular Ageing

open access: yesCell Proliferation, EarlyView.
We observed a range of age‐related modifications in testicular morphology and spermatogenic cells during ageing, and conducted scRNA‐seq on testes, establishing a foundational comprehension of mitochondrial dysfunction as a basis for testicular ageing.
Weijie Xu   +18 more
wiley   +1 more source

HN1 Functions in Protein Synthesis Regulation via mTOR‐RPS6 Axis and Maintains Nucleolar Integrity

open access: yesCell Proliferation, EarlyView.
HN1 is required for nucleolar homeostasis which is the site of ribosome biogenesis and protein synthesis when its mRNA is knocked down by shRNA, it depletes in cytoplasm and the protein synthesis is downregulated in comparison to controls. Thus, the proliferating cells requiring vast number of nucleosomes, are arrested at S onset.
Gülseren Özduman   +4 more
wiley   +1 more source

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