Results 81 to 90 of about 175,876 (284)

TGF-β Signaling Interferes With the Drosophila Innate Immune and Metabolic Response to Parasitic Nematode Infection

Frontiers in Physiology, 2019
The common fruit fly, Drosophila melanogaster, is an outstanding model to study the molecular basis of anti-pathogen immunity. The parasitic nematode Heterorhabditis gerrardi, together with its mutualistic bacteria Photorhabdus asymbiotica, infects a ...
Yaprak Ozakman, Ioannis Eleftherianos
doaj   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

Neuroprotective Effect and Mechanism of Xanthoceras sorbifolium Oil on Drosophila melanogaster with Alzheimer's Disease

Shipin gongye ke-ji
This study aimed to investigate the neuroprotective effect of Xanthoceras sorbifolium oil (XSO) on the Drosophila melanogaster model of Alzheimer's disease (AD) and to explore the underlying mechanism.
Chenyao XIANG, Duoduo REN, Xuejun CHAI, Jiayue WU, Xiaofan LIU, Yuyu ZHAO, Yongkang ZHAO, Xiaoyan ZHU, Shanting ZHAO   +8 more
doaj   +1 more source

RNAseq Analysis of the Drosophila Response to the Entomopathogenic Nematode Steinernema

G3: Genes, Genomes, Genetics, 2017
Drosophila melanogaster is an outstanding model to study the molecular and functional basis of host–pathogen interactions. Currently, our knowledge of microbial infections in D.
Shruti Yadav, Sean Daugherty, Amol Carl Shetty, Ioannis Eleftherianos   +3 more
doaj   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

Developmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim, You‐Lim Hwang, Sunwoo Yeom, Seung‐Hae Kwon, Sang‐Hak Jeon   +4 more
wiley   +1 more source

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

Developmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe, Yu Chen, Geoff Shaw, Marilyn B. Renfree   +3 more
wiley   +1 more source

BKCa (Slo) Channel Regulates Mitochondrial Function and Lifespan in Drosophila melanogaster [PDF]

, 2019
Shubha Gururaja Rao, Piotr Bednarczyk, Atif Towheed, Kajol Shah, Priyanka Karekar, Devasena Ponnalagu, Haley N. Jensen, Sankar Addya, Beverly A.S. Reyes, Elisabeth J. Van Bockstaele, Adam Szewczyk, Douglas C. Wallace, Harpreet Singh   +12 more
openalex   +1 more source

The Status and Emerging Developments in Laboratory Animal Science in Asia since 9th AFLAS Congress (2023) until 10th AFLAS Congress (2025)

Animal Models and Experimental Medicine, EarlyView.
Asian Federation of Laboratory Animal Science Associations (AFLAS)
wiley   +1 more source

Single‐cell sequencing reveals potential novel insights into appendage‐patterning and joint‐development in a spider

Developmental Dynamics, EarlyView.
Abstract Background Jointed appendages represent one of the key innovations of arthropods, and thus understanding the development and evolution of these structures is important for the understanding of the evolutionary success of Arthropoda. In this paper, we analyze a cell cluster that was identified in a previous single‐cell sequencing (SCS ...
Brenda I. Medina‐Jiménez, Graham E. Budd, Ralf Janssen   +2 more
wiley   +1 more source

Molecular and functional characterization of the Drosophila melanogaster conserved smORFome

, 2023
Justin A. Bosch, Nathan Keith, Felipe Escobedo, William W. Fisher, James Thai LaGraff, Jorden Rabasco, Kenneth H. Wan, Richard Weiszmann, Yulun Wu, Yanhui Hu, Shu Kondo, James B. Brown, Norbert Perrimon, S Celniker   +13 more
openalex   +1 more source