Results 241 to 250 of about 458,085 (304)

Microfluidics‐Based Microcarriers for Live‐Cell Delivery

open access: yesAdvanced Science, EarlyView.
In this review, recent advancements in microfluidics‐based microcarriers for live‐cell delivery are highlighted. The structural designs of microfluidic‐derived cell‐laden microcarriers are systematically categorized, emphasizing innovative approaches in the fabrication of microspheres, microfibers, and microneedles.
Zhonglin Fang   +3 more
wiley   +1 more source

Primary malignant melanoma of the tongue.A case report and review of the literature [PDF]

open access: bronze, 1965
Jerry J. Principato   +2 more
openalex   +1 more source

A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma

open access: yesAdvanced Science, EarlyView.
The TPC@OVA NPs are developed as dual‐functional nanomaterials combining phototherapy and immunotherapy for melanoma treatment. This system effectively ablates primary tumors, induces immunogenic cell death, promotes dendritic cell maturation, and enhances T cell activation.
Zhuang Fan   +6 more
wiley   +1 more source

Reshape the Fates of Treg and CD8+T Cells Through IL‐2Rα by Synergizing Divergent Receptor‐Biased IL‐2 PEGylates

open access: yesAdvanced Science, EarlyView.
This study presents receptor‐biased IL‐2 PEGylates that selectively modulate IL‐2 receptor subunit interactions to enhance CD8⁺ T cell antitumor activity while curbing Treg activation and endothelial toxicity. The combined not‐α and not‐β variants balance immune stimulation and prevent T cell exhaustion, offering a novel, fine‐tuned approach for ...
Jiaqi Sun   +23 more
wiley   +1 more source

Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) extracellular vesicle (EV) surface protein assay operates via a two‐step workflow – Step 1: Click chemistry‐mediated enrichment of PDAC EVs by EV Click Beads, in the presence of one of the three trans‐cyclooctene‐grafted PDAC EV‐specific antibodies; Step 2: Quantification of the enriched PDAC EVs by reverse ...
Chen Zhao   +27 more
wiley   +1 more source

Differential Diagnosis of Melanoma [PDF]

open access: gold, 1965
Gordon McNeer, T. D. Gupta
openalex   +1 more source

A Methionine Allocation Nanoregulator for the Suppression of Cancer Stem Cells and Support to the Immune Cells by Epigenetic Regulation

open access: yesAdvanced Science, EarlyView.
A nanoregulator interfering with intratumoral methionine competition is designed to deliver oxaliplatin (IV) prodrugs and anti‐Lat4 small interfering RNA to tumor cells. This Pt (IV)‐crosslinked reduction‐sensitive nanoregulator progressively releases drugs within tumor cells and induces immunogenic cell death.
Boyu Su   +14 more
wiley   +1 more source

Mannose‐Glycated Metal‐Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Immunomodulatory metal‐phenolic microcapsules (mMPMs) is developed in this study that leverages dopamine‐modified hyaluronic acid and FeIII assemble on mannose‐glycated bovine serum albumin microbubbles. mMPMs effectively promote macrophage internalization and M1 polarization, enhancing pro‐inflammatory responses.
Xin Tan   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy