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Surgical Pathology Clinics, 2009
This article discusses the key features of nevoid melanoma. Gross features, microscopic features, immunohistochemistry, differential diagnosis, diagnosis, prognosis, and treatment are also discussed.
A Hafeez, Diwan, Alexander J, Lazar
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This article discusses the key features of nevoid melanoma. Gross features, microscopic features, immunohistochemistry, differential diagnosis, diagnosis, prognosis, and treatment are also discussed.
A Hafeez, Diwan, Alexander J, Lazar
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Melanoma Update Second Primary Melanoma
The Journal of Dermatologic Surgery and Oncology, 1993BACKGROUND. Second primary melanoma is not a rare phenomenon. It occurs in at least 3 to 6% of melanoma patients and up to a third of individuals from melanoma‐prone families.OBJECTIVE. To review the clinical and histologic features of multiple primary melanoma. A schema for follow‐up of these patients is presented.CONCLUSIONS.
W, Frank, G S, Rogers
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Cancer Investigation, 2002
The identification of antigens on tumor cells has led to significant contributions to the field of immunotherapy. One of the most active areas under investigation in cancer immunotherapy is the development of vaccines against melanoma antigens. Induction of immunity against tumor antigens can follow multiple routes using different mechanisms.
Miguel-Angel, Perales, Jedd D, Wolchok
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The identification of antigens on tumor cells has led to significant contributions to the field of immunotherapy. One of the most active areas under investigation in cancer immunotherapy is the development of vaccines against melanoma antigens. Induction of immunity against tumor antigens can follow multiple routes using different mechanisms.
Miguel-Angel, Perales, Jedd D, Wolchok
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Clinics in Laboratory Medicine, 2009
Desmoplastic melanoma (DM) is a variant of spindle cell melanoma characterized by the presence of abundant fibrous matrix. It is typically found in the head and neck region on chronically sun-damaged skin of older individuals. Early detection is uncommon, because its clinical features are not distinctive. DM is prone to misdiagnosis not only clinically
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Desmoplastic melanoma (DM) is a variant of spindle cell melanoma characterized by the presence of abundant fibrous matrix. It is typically found in the head and neck region on chronically sun-damaged skin of older individuals. Early detection is uncommon, because its clinical features are not distinctive. DM is prone to misdiagnosis not only clinically
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Advances in Anatomic Pathology, 2014
On the basis of a critical review of published literature, it is concluded that there is as yet insufficient evidence to conclude that the melanocytic lesion, which is currently known as "lentiginous melanoma," is a full-fledged melanoma, with the capacity to metastasize to distant sites and to cause the demise of the patient.
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On the basis of a critical review of published literature, it is concluded that there is as yet insufficient evidence to conclude that the melanocytic lesion, which is currently known as "lentiginous melanoma," is a full-fledged melanoma, with the capacity to metastasize to distant sites and to cause the demise of the patient.
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Clinical and Experimental Dermatology, 1992
The presence of large numbers of moles, atypical in appearance and distribution typifies the atypical mole syndrome. The syndrome may occur in one individual alone or in an autosomal-dominant fashion in his/her family. The presence of this phenotype indicates an increased risk of melanoma, although the risk varies according to the presence or absence ...
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The presence of large numbers of moles, atypical in appearance and distribution typifies the atypical mole syndrome. The syndrome may occur in one individual alone or in an autosomal-dominant fashion in his/her family. The presence of this phenotype indicates an increased risk of melanoma, although the risk varies according to the presence or absence ...
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Journal of the American Academy of Dermatology, 1984
Cutaneous inflammatory metastatic carcinoma is a well-documented entity most frequently associated with carcinoma of the breast. We present two patients with extensive inflammatory involvement of the skin overlying dermal lymphatic invasion by metastatic melanoma.
H M, Haupt, A F, Hood, M H, Cohen
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Cutaneous inflammatory metastatic carcinoma is a well-documented entity most frequently associated with carcinoma of the breast. We present two patients with extensive inflammatory involvement of the skin overlying dermal lymphatic invasion by metastatic melanoma.
H M, Haupt, A F, Hood, M H, Cohen
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Current Oncology Reports, 2004
Sophisticated molecular techniques that have recently become available permit analysis of genome-wide changes in gene copy number (DNA) or expression (RNA). These genomic strategies have the potential to transform our view of cancer biology and pathogenesis.
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Sophisticated molecular techniques that have recently become available permit analysis of genome-wide changes in gene copy number (DNA) or expression (RNA). These genomic strategies have the potential to transform our view of cancer biology and pathogenesis.
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Surgical Clinics of North America, 2008
Approximately 5% to 10% of cases of cutaneous melanoma occur in families that have a hereditary predisposition for this disease. In 20% to 40% of such melanoma families, germline mutations in the CDKN2A gene have been identified. Apart from a high risk of melanoma, a proportion of kindreds that have familial melanoma also have an increased risk of ...
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Approximately 5% to 10% of cases of cutaneous melanoma occur in families that have a hereditary predisposition for this disease. In 20% to 40% of such melanoma families, germline mutations in the CDKN2A gene have been identified. Apart from a high risk of melanoma, a proportion of kindreds that have familial melanoma also have an increased risk of ...
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