Results 81 to 90 of about 4,950 (170)
The pigment cells of vertebrates serve a variety of functions and generate a stunning variety of patterns. These cells are also implicated in human pathologies including melanoma.
Erine H Budi +2 more
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Vertebrate melanophores as potential model for drug discovery and development: A review
Drug discovery in skin pharmacotherapy is an enormous, continually expanding field. Researchers are developing novel and sensitive pharmaceutical products and drugs that target specific receptors to elicit concerted and appropriate responses. The pigment-
Saima Salim, Sharique Ali
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The zebrafish adult pigment pattern has emerged as a useful model for understanding the development and evolution of adult form as well as pattern-forming mechanisms more generally.
Dae Seok Eom +7 more
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A role for spectrin in dynactin-dependent melanosome transport in Xenopus laevis melanophores
The bi-directional movement of pigment granules in frog melanophores involves the microtubule-based motors cytoplasmic dynein, which is responsible for aggregation, and kinesin II and myosin V, which are required for dispersion of pigment.
Wallin, Margareta,, Aspengren, Sara,
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Transparent immunodeficient animal models not only enhance in vivo imaging investigations of visceral organ development but also facilitate in vivo tracking of transplanted tumor cells.
Rensen Ran +5 more
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Heterotypic interactions regulate cell shape and density during color pattern formation in zebrafish
The conspicuous striped coloration of zebrafish is produced by cell-cell interactions among three different types of chromatophores: black melanophores, orange/yellow xanthophores and silvery/blue iridophores.
Prateek Mahalwar +4 more
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Understanding the ultrastructural aspects of berberine-induced skin-darkening activity in the toad, Bufo melanostictus, melanophores [PDF]
Berberine is an active compound of Berberis vulgaris (Daruhaldi) with known multiple pharmacological activities, including antimicrobial, antiviral, anti-inflammatory, cholesterol-lowering, and anticancer effects.
Ali, Sharique A., Naaz, Ishrat
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Myosin cooperates with microtubule motors during organelle transport in melanophores [PDF]
Melanophores offer an outstanding system for the study of intracellular motility. These cells aggregate their pigment-filled melanosomes to the cell center or disperse them throughout the cytoplasm in response to hormonal modulation of intracellular ...
Rogers, Stephen L, Gelfand, Vladimir I
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Height changes associated with pigment aggregation in Xenopus laevis melanophores
Melanophores are pigment cells found in the skin of lower vertebrates. The brownish-black pigment melanin is stored in organelles called melanosomes. In response to different stimuli, the cells can redistribute the melanosomes, and thereby change colour.
Magnusson, Karl-Eric, +5 more
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alpha-Melanocyte-stimulating hormone (alpha-MSH) is a member of the melanocortin (MC) family, and the MC receptor (MCR) is a member of the G protein-coupled receptor (GPCR) superfamily.
Schiöth, Helgi B., +4 more
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