Results 61 to 70 of about 7,402 (172)

Receptor‐Targeted Niosomal Nanocarriers: Advances, Challenges, and Opportunities in Natural Compound Delivery for Cancer Therapy

open access: yesNano Select, Volume 7, Issue 10, October 2026.
Surface‐modified niosomes are introduced as multifunctional nanoparticles for precision tumor treatment that combine hydrophilic and lipophilic drug encapsulation with ligand‐based targeting via antibodies, peptides, transferrin, and folic acid. This modification leads to increased tumor selectivity, facilitates cell entry, and enables enhanced ...
Narges Sahraei   +3 more
wiley   +1 more source

Chlorine Position Governs the Multitarget Bioactivity of Phenylhydrazines: In Vitro Antioxidant, Anti‐Inflammatory, Anti‐Tyrosinase and Antibacterial Evaluation Supported by DFT and Molecular Docking

open access: yesChemistrySelect, Volume 11, Issue 37, 6 October 2026.
Positional chlorination emerges as a key determinant of multitarget activity in phenylhydrazines. The para‐chloro derivative H3 shows the strongest anti‐inflammatory response, notable antibacterial activity, favorable ADMET behavior, and high COX‐2 affinity. DFT descriptors and molecular docking rationalize these substitution‐dependent effects, linking
L. Aouachria   +8 more
wiley   +1 more source

Investigating the Relationship Between Serum Thyroid Hormone and Vitamin D Levels in Women with Melasma

open access: yesAl-SalamJournal for Medical Science
Patches and macules of hyperpigmentation characterize melasma, a prevalent condition of skin pigmentation. Known risk factors for melasma include a genetic predisposition, sun exposure, and pregnancy.
Majeed Ali Fahad
doaj   +3 more sources

A Prediction Model for the Differential Diagnosis of Bowen's Disease and Bowenoid Actinic Keratosis

open access: yesThe Journal of Dermatology, Volume 53, Issue 10, Page 1465-1473, October 2026.
ABSTRACT Bowen's disease and bowenoid actinic keratosis share overlapping clinical and histopathological features, and there is no clear consensus regarding their differential diagnosis. This study aimed to identify clinicopathological differences between the two diseases and to develop a diagnostic prediction model in a Korean population.
Byeonghyun Joo   +6 more
wiley   +1 more source

Association of lentigo, freckle, melanicytic nevus with melasma [PDF]

open access: yes
Background and aim: It seems that melanocytic nevi, freckle and lentigo are more common in women with melasma, and a common genetic background may exist.
امینی ثانی, نیره   +2 more
core  

Melasma update

open access: yes, 2014
Melasma is an acquired pigmentary disorder characterized by symmetrical hyperpigmented macules on the face. Its pathogenesis is complex and involves the interplay of various factors such as genetic predisposition, ultraviolet radiation, hormonal factors,
Rashmi Sarkar   +4 more
core   +1 more source

What should be considered in treatment of melasma. [PDF]

open access: yes, 2010
Melasma is a common acquired hyperpigmentary skin disorder characterized by light to dark brown macules and patches occurring in the sun-exposed areas of the face.
Ortonne, JP   +3 more
core   +1 more source

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

open access: yesJournal of Cutaneous Pathology, Volume 53, Issue 10, Page 887-892, October 2026.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua   +4 more
wiley   +1 more source

Melasma: A Clinical and Epidemiological Single-Group Observational Study in the Greek Population

open access: yesDermatology and Therapy
Introduction Melasma is a common acquired disorder of melanogenesis that predominately affects women and presents as hyperpigmented skin lesions mainly located on the face.
Eftychia Platsidaki   +6 more
doaj   +1 more source

The association between melasma and iron profile: a case-control study

open access: yesRussian Open Medical Journal, 2020
Background — Melasma is a chronic acquired localized hypermelanosis, causing aesthetic problem for women and impairing their quality of life. Evidence has suggested that hyperpigmentation can occur as a result of iron deficiency anemia and vitamin B12 ...
Azadeh Goodarzi   +6 more
doaj   +1 more source

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