Results 61 to 70 of about 174,022 (169)

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues

Bioactive Materials, 2023
Periodontitis is a chronic inflammatory condition that often causes serious damage to tooth-supporting tissues. The limited successful outcomes of clinically available approaches underscore the need for therapeutics that cannot only provide structural ...
Arwa Daghrery, Jessica A. Ferreira, Jinping Xu, Nasim Golafshan, Darnell Kaigler, Sarit B. Bhaduri, Jos Malda, Miguel Castilho, Marco C. Bottino   +8 more
doaj   +1 more source

3D printing of cell‐free implants: A promising avenue for cartilage regeneration and joint preservation

Interdisciplinary Medicine, EarlyView.
This article explores the potential of 3D‐printed, cell‐free implants or devices for cartilage regeneration. It highlights the benefits of using biomaterial‐driven activation and modulation of ESCPs for endogenous healing of heterogeneous tissues, addressing challenges in implant design, repair mechanisms, and regulatory hurdles to create scalable ...
Liangbin Zhou, Shangsi Chen, Boguang Yang, Yiting Lei, Hegeng Li, Haoyue Luo, Xiaoshuai Wang, Qiongjiao Zeng, Jiahui Lai, Fei Jin, Rocky S. Tuan, Zhong Alan Li   +11 more
wiley   +1 more source

3D in vitro modeling of neural microenvironment through a multi-scaffold assembly approach

Materials Today Bio
The engineering of in vitro 3D cell culture systems has emerged as promising approach to model central nervous system (CNS) intricacy with increasing physiological relevance.
Cecilia Traldi, Vanessa Chiappini, Silvia Chasseur, Federica Aiello, Marina Boido, Chiara Tonda-Turo   +5 more
doaj   +1 more source

Alignment of Micrometer‐Scale Electrospun Fibers Does Not Enhance Performance of Primary Human Renal Proximal Tubular Epithelial Cells

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 9, September 2026.
ABSTRACT Renal failure remains a leading cause of morbidity and mortality, as current renal replacement therapies restore filtration but fail to replicate the kidney's transport, metabolic, and endocrine functions. Bioengineered systems using primary renal epithelial cells show promise in recapitulating these processes, and integration into synthetic ...
IJsbrand M. Vermue, Christian G. M. van Dijk, Ihsan Chrifi, Ymke Appels, Jurjen van Meijeren, Bastiaan Terhaard, Nahid Kasaiyan, Marianne C. Verhaar, Caroline Cheng   +8 more
wiley   +1 more source

MXene Bioinks for 3D Bioprinting: Design and Translation

Small, Volume 22, Issue 50, 7 September 2026.
This study establishes a comprehensive framework for MXene‐based bioinks in 3D bioprinting, highlighting the interplay between rheological engineering and electroactive hydrogels. By optimizing electrical percolation and mediated signaling, these formulations drive tissue‐specific biological outcomes and accelerated regeneration.
Begüm Sarac, Seydanur Yücer, Fatih Ciftci   +2 more
wiley   +1 more source

Channelized melt flow in downwelling mantle: Implications for 226Ra-210Pb disequilibria in arc magmas [PDF]

, 2008
We present the results of an analytical model of porous flow of viscous melt into a steadily dilating ‘‘channel’’ (defined as a cluster of smaller veins) in downwelling subarc mantle.
Koenders, M. A., Petford, Nick; id_orcid, Koenders, M.A., Petford, N., Turner, S, Petford, Nick, Turner, S., Koenders, M A   +7 more
core   +1 more source

‐glycolic acid) Microfibers via Melt Electrowriting

, 2022
Polymers sensitive to thermal degradation include poly(lactic-co-glycolic acid) (PLGA), which is not yet processed via melt electrowriting (MEW). After an initial period of instability where mean fiber diameters increase from 20.56 to 27.37 µm in 3.5 h ...
Böhm, Christoph, Teßmar, Jörg, Biranche Tandon, Hrynevich, Andrei, Christoph Böhm, Dalton, Paul D., Jörg Teßmar, Andrei Hrynevich, Tandon, Biranche, Paul D. Dalton   +9 more
core   +1 more source

Multifunctional Wound Dressings: Melt Electrowritten Scaffolds Combined With Phytotherapeutic Composite Hydrogels

Advanced Materials Interfaces, Volume 13, Issue 16, 18 August 2026.
ABSTRACT The increasing prevalence of impaired wounds, caused mainly by diabetes or aging, alongside the growing number of bacterial infections, indicates the need for alternative tissue engineering solutions. In this study, we developed novel melt electrowritten (MEW) polycaprolactone (PCL) scaffolds incorporated with an alginate (Alg)–gelatin (Gel ...
Andrada‐Ioana Damian‐Buda, Aldo Roberto Boccaccini, Irem Unalan   +2 more
wiley   +1 more source