Results 111 to 120 of about 12,198,711 (338)
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Acta Agriculturae Slovenica, 2009 We explored existing primer sequences targeting nitrous oxide reductase (nosZ) gene in order to explore their capability to recognize variant nosZ sequences. Published nosZ sequences longer than 380 AA residues were obtained from FunctionalGene Database /
Blaž STRES, Boštjan MUROVEC
doaj +1 more source
Apparent melting temperature of concatameric proteins.
, 2012 Apparent melting temperature of concatameric proteins.
Eric G. Huizinga (159354) +1 more
core +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li +7 more
wiley +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Gold Nanoparticle Melting: Effects of Size, Support Interaction, and Orientation
Small StructuresAn understanding of nanoparticle (NP) melting is essential for both fundamental nanoscience and the design of high‐temperature catalytic systems. We investigate the melting behavior of truncated octahedral gold NPs, ranging in size from 2 to 4 nm ...
Th. Pavloudis +3 more
doaj +1 more source
Can Pseudotachylytes Form via Fracture-Induced Decompression Melting Under Hydrous Conditions?
TektonikaFrictional rock sliding and resultant shear heating along a fault plane are proposed as the necessary conditions to generate earthquake-related pseudotachylytes.
Mattia Pistone +4 more
doaj +1 more source
THERMODYNAMIC APPROACH TO THE PROBLEM OF THE SIZE DEPENDENCE OF THE THIN FILM MELTING TEMPERATURE [PDF]
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2012 Size dependences of the melting temperature for supported thin films were calculated using relations obtained earlier. A conclusion is made that the most noticeable size effect should be expected when the film is characterized by the anomalous ...
V.M. Samsonov +3 more
doaj