Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Estimated unit costs of anaemia interventions for women of reproductive age in 193 UN member states: a costing study. [PDF]
Oliver VL +8 more
europepmc +1 more source
Supporting the Manufacturing of Medical Supplies in Africa: Collaboration Between Africa CDC, Partners, and Member States. [PDF]
Mohammed A +13 more
europepmc +1 more source
A.3. Workshop: Directive 2011/24/EU: a framework for cooperation between member states [PDF]
Chairperson: Helmut Brand, The Netherlands
openalex +1 more source
Regional policy, convergence and subsidiarity in the European Community [PDF]
The aim of this paper is to shed light on how real income has developed across the member states and regions of the EC and to consider what demands this will place on regional policy.
Thomas, Ingo P.
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Current status of radiologist staffing, education and training in the 27 EU Member States. [PDF]
Brady AP +6 more
europepmc +1 more source
Inequity of maternal-child health services in ASEAN member states from 1993 to 2021. [PDF]
Feng Y +6 more
europepmc +1 more source
Determinants of Job Creation in Eleven New EU Member States: Evidence from Firm Level Data
Harald Oberhofer +1 more
openalex +2 more sources
FINANCIAL CONFIGURATIONS AND INTERACTIONS IN A TRANSFORMATION PROCESS OF A GLOBAL ECONOMY [PDF]
This article aims to present the summary of issues related to Economic and Monetary Union (EMU) in the context of EU enlargement, analyzing legal rules and practical problems appeared.
PĂUN, Roxana-Daniela
core

