Results 91 to 100 of about 765,979 (297)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

A Novel Hybrid Symbolic Fuzzy Interval-Based Clustering Approach for Microarray Image Spot Segmentation

IEEE Access
Microarray image analysis is an algorithmic and analytical approach used in gene expression profiling in the study of biological and zoological taxonomy.
C. K. Roopa, B. S. Harish, M. P. Priya, Francesco Flammini   +3 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Multilevel Fuzzy Inference System for Estimating Risk of Type 2 Diabetes

Mathematics
In this paper, we present a multilevel fuzzy inference model for predicting the risk of type 2 diabetes. We have designed a system for predicting this risk by taking into account various factors such as physical, behavioral, and environmental parameters ...
Jelena Tašić, Zsófia Nagy-Perjési, Márta Takács   +2 more
doaj   +1 more source

Influence of machine learning membership functions and degree of membership function on each input parameter for simulation of reactors. [PDF]

Sci Rep, 2021
Pelalak R, Nakhjiri AT, Marjani A, Rezakazemi M, Shirazian S.   +4 more
europepmc   +1 more source

Learning control of inverted pendulum system by neural network driven fuzzy reasoning: The learning function of NN-driven fuzzy reasoning under changes of reasoning environment [PDF]

Whereas conventional fuzzy reasonings are associated with tuning problems, which are lack of membership functions and inference rule designs, a neural network driven fuzzy reasoning (NDF) capable of determining membership functions by neural network is ...
Hayashi, Isao, Nomura, Hiroyoshi, Wakami, Noboru   +2 more
core   +1 more source

Derivatives of rational inner functions: geometry of singularities and integrability at the boundary

, 2017
We analyze the singularities of rational inner functions on the unit bidisk and study both when these functions belong to Dirichlet-type spaces and when their partial derivatives belong to Hardy spaces.
Bickel, Kelly, Pascoe, James Eldred, Sola, Alan   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source