Results 141 to 150 of about 5,362,504 (373)
Membrane proteins and membrane structure [PDF]
David E. Green, Roderick A. Capaldi
openaire +3 more sources
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu+3 more
wiley +1 more source
Dynamics of non-equilibrium membrane bud formation
The dynamical response of a lipid membrane to a local perturbation of its molecular symmetry is investigated theoretically. A density asymmetry between the two membrane leaflets is predominantly released by in-plane lipid diffusion or membrane curvature,
B. Alberts+8 more
core +1 more source
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou+13 more
wiley +1 more source
Finite Membrane Thickness Influences Hydrodynamics on the Nanoscale [PDF]
Many lipid membrane-mediated transport processes--such as mechanically-gated channel activation and solute transport--involve structural and dynamical features on membrane thickness length scales. Most existing membrane models, however, tend to adopt (quasi-)two-dimensional descriptions that neglect thickness-dependent phenomena relevant to internal ...
arxiv
Calculable membrane theory [PDF]
The key to membrane theory is to enlarge the diffeomorphism group until 4D gravity becomes almost topological. Just one ghost survives and its central charges can cancel against matter. A simple bosonic membrane emerges, but its flat D = 28 target space is unstable.
arxiv
SCLEROSIS OF THE MUCOUS MEMBRANE OF THE NYMPHÆ AND VESTIBULE. [PDF]
James Oliver
openalex +1 more source
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad+13 more
wiley +1 more source
CRC 1114 - Report Membrane Deformation by N-BAR Proteins: Extraction of membrane geometry and protein diffusion characteristics from MD simulations [PDF]
We describe simulations of Proteins and artificial pseudo-molecules interacting and shaping lipid bilayer membranes. We extract protein diffusion Parameters, membrane deformation profiles and the elastic properties of the used membrane models in preparation of calculations based on a large scale continuum model.
arxiv
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran+16 more
wiley +1 more source