Results 231 to 240 of about 5,417,341 (315)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Expanding Beyond Water-Based Percrystallization: Assessment of Active Pharmaceutical Ingredients Processing and Solvent Recovery. [PDF]

ACS Omega
Sequeira CB, Diniz da Costa JC, Henriques A, Duarte MT, Crespo JG.   +4 more
europepmc   +1 more source

Magnetically Targeted Drug Transport Across a Tumor Cell Membrane Under Magnetic Field Gradients. [PDF]

Int J Mol Sci
Kovačević MS, Dragnić R, Marković VM, Kovačević I, Tosi D.   +4 more
europepmc   +1 more source

Cytoplasmic expression of laminin-5γ2 chain is associated with progression and acquisition of malignant traits in ovarian serous and mucinous tumors. [PDF]

Medicine (Baltimore)
Tajika Y, Imura J, Noguchi A, Orita M, Nakajima Y, Minamisaka T, Takagi K, Shima T, Nakashima A, Hirabayashi K.   +9 more
europepmc   +1 more source

Long-range mutual activation establishes Rho and Rac polarity during cell migration. [PDF]

Nat Cell Biol
De Belly H, Gallén AF, Strickland E, Estrada DC, Godinez DS, Neiva E, Zager PJ, Nagy TL, Burkhardt JK, Turlier H, Weiner OD.   +10 more
europepmc   +1 more source

Membrane curvature enhances oxidation within lipid bilayers in a composition-dependent manner. [PDF]

Biophys J
Kim J, Bartholomew SN, Zeno WF.
europepmc   +1 more source

The penta-EF-hand protein Pef1 of Candida albicans functions at sites of membrane perturbation to support polarized growth and membrane integrity. [PDF]

G3 (Bethesda)
Weichert M, Schumann MR, Brandt U, Bedford C, Brand AC, Fleißner A.   +5 more
europepmc   +1 more source