Results 281 to 290 of about 5,646,580 (347)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Cell Membrane (Plasma Membrane) [PDF]

, 2019
openaire   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Serotonergic Signaling Rewired: A Lipid Raft-Controlled Model of Synaptic Transmission Grounded in the Fundamental Parameters of Biological Systems. [PDF]

Life (Basel)
Fantini J, Lefebvre M, Yahi N, Chahinian H.   +3 more
europepmc   +1 more source

Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation. [PDF]

Nat Commun
Dahmane S, Schexnaydre E, Zhang J, Singh BK, Rosendal E, Chotiwan N, Sharma KB, Nilsson E, Peters MBA, Yau WL, Rönfeldt S, Lundmark R, Barad BA, Grotjahn DA, Liese S, Carlson A, Överby AK, Carlson LA.   +17 more
europepmc   +1 more source

Clathrins Are Involved in the Endocytosis of Host Cytosol in the Malaria Parasite. [PDF]

Traffic
Miao J, Lucky AB, Ning G, Xia X, Liang X, Siddiqui F, Min H, Wang C, Li X, Zhou ZH, Cui L.   +10 more
europepmc   +1 more source

Antifungal Activity of Natural Thymol: Advances on Molecular Mechanisms and Therapeutic Potential. [PDF]

Biomolecules
Chen C, Liu L, Tang S, Li D, Dai C.
europepmc   +1 more source

COF Scaffold Membrane with Gate-Lane Nanostructure for Efficient Li⁺/Mg²⁺ Separation. [PDF]

Nanomicro Lett
Zhang Z, Kong Y, Li R, Yue X, Deng H, Zheng Y, Zhang S, Zhang R, Jiang Z.   +8 more
europepmc   +1 more source

A generalized fractional model for one-step identification of membrane filtration clogging mechanisms. [PDF]

Sci Rep
Cherifi L, Ammi Y, Hanini S, Bailek N, El-Kenawy EM, Younis JA, Zerouali B, Dahmani A, Colak I, Almaliki AH.   +9 more
europepmc   +1 more source