Results 141 to 150 of about 1,241,158 (299)
Neuromorphic Devices and Computing for Sensing, Memory, and Control
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu +2 more
wiley +1 more source
Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley +1 more source
Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao +5 more
wiley +1 more source
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang +9 more
wiley +1 more source
B Pevan Kumar, M Saravanan
openaire +1 more source
An innovative application of membrane contactors: the vacuum membrane dryer
An innovative application of membrane contactors is presented in this work. The study focused on the use of Vacuum Membrane Distillation (VMD) for the dehydration of an aqueous solution containing solid polystryrene microparticles (7 micron).
MC Carnevale +3 more
core
Herbivory‐Induced Stomatal Opening Triggers the Dispersal of an Invasive Insect Herbivore
The invasive leafminer Phthorimaea absoluta uniquely manipulates plant defenses by inducing stomatal opening in tomato. This response, mediated by the stomatal regulator IQM1, enhances the release of the repellent volatile benzaldehyde. This volatile triggers the dispersal of adult moths, facilitates colonization of new hosts, and leads to rapid ...
Limin Chen +10 more
wiley +1 more source
A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias +23 more
wiley +1 more source
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang +12 more
wiley +1 more source
Carbonate crystallization via vacuum membrane distillation-crystallization
Although crystallization processes are part of the most basic separation and purification processes in the chemical industry, they still present considerable difficulties at large scale because of the complex kinetics, fluido-dynamics and supersaturation
12th International Congress on Membranes & Membrane Processes 2020 (ICOM2020) +2 more
core

