Results 181 to 190 of about 2,406,558 (338)

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Photothermal carbon black coatings enable efficient solar-driven membrane distillation. [PDF]

RSC Adv
Alshareef M, Mahmoud AM, Al-Ghamdi AS, Alhumade H, Mustafa I, Alotaibi MT, Alharbi A, Ebraheem B, Ali MEA.   +8 more
europepmc   +1 more source

Membrane distillation at the water-energy nexus: limits, opportunities, and challenges

, 2018
Akshay Deshmukh, Chanhee Boo, V. Karanikola, Shihong Lin, Anthony P. Straub, Tiezheng Tong, D. Warsinger, M. Elimelech   +7 more
semanticscholar   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

Enhanced water desalination via PVDF-chabazite mixed matrix membranes in vacuum membrane distillation. [PDF]

Sci Rep
Plata-Gryl M, Galiano F, Russo F, Abed RB, Figoli A, Gläser R, Castro-Muñoz R.   +6 more
europepmc   +1 more source

Applications of osmotic distillation in food and wine processing: the critical points, their weaknesses and the potentialities

, 2011
In this work some application of Osmotic Distillation are reviewed discussed. The first application concerns the concentration of juices at room temperature by using downstream the membrane a mixture with low water activity, so that water vapour diffuses
GOSTOLI, CARLO, R. Ferrarini
core  

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Impacts of variable operating conditions on flux and energy efficiency of air gap membrane distillation for brine management. [PDF]

Sci Rep
Mohamed ES, Azzam AM, Mohamed AT, Ragab A, Ahmed G, Sheta O, Kamel MS, Seif E, El-Batt T.   +8 more
europepmc   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Effects of Metal Foam Insertion on the Performance of a Vacuum Membrane Distillation Unit. [PDF]

Membranes (Basel)
Loussif N, Orfi J.
europepmc   +1 more source