Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng +15 more
wiley +1 more source
Magnesium Recovery from Nanofiltration Brine by Membrane Distillation Crystallization. [PDF]
Saud A, Ali A, Quist-Jensen CA.
europepmc +1 more source
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang +11 more
wiley +1 more source
Systematic Material Optimization for Membrane Distillation Resource Recovery through Materials Informatics, Life Cycle Assessment, and Industrial Scalability. [PDF]
Merugu S, Suthar KB, Gupta A.
europepmc +1 more source
Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran +10 more
wiley +1 more source
Comprehensive dataset on macro-porous PVDF flat sheet membranes for membrane distillation: Materials characteristics, morphology and performance data. [PDF]
Bohr SJ +7 more
europepmc +1 more source
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng +10 more
wiley +1 more source
Simultaneously Boosting Freshwater Productivity and Antifouling Efficacy of Membrane Distillation Through In Situ Micro-Bubble Generation. [PDF]
Li Z, Akhtar FH, Cui X, Wang X, Chen Q.
europepmc +1 more source
Dual Repression by IPA1 Fine‐Tunes OsbZIP79‐Mediated Salt Tolerance in Rice
Dual repression by IPA1 fine‐tunes OsbZIP79‐mediated salt tolerance in rice: direct transcriptional inhibition under normal conditions and salt‐induced degradation under stress. This dual mechanism activates OsbZIP79 to regulate Na+/K+ homeostasis and redox balance via downstream genes, enabling optimal salt stress response.
Hui Wang +12 more
wiley +1 more source
Anti-Wetting PVDF Membrane Modification by Coating Fluoride and Deposing Different Silicon Contents for Membrane Distillation Treatment of Ammonia Nitrogen Wastewater. [PDF]
Liu Q +5 more
europepmc +1 more source

