Results 41 to 50 of about 276,575 (262)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
CHIMIA, 2020 Membrane filtration applications are omnipresent in production processes of the food and beverage industry, in pharmaceutical production and the petrochemical industry but also in water purification for drinking water production and wastewater ...
Kirsten Remmena, Joachim Koeserb
doaj +1 more source
Stochastic modelling of membrane filtration [PDF]
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2017 Membrane fouling during particle filtration occurs through a variety of mechanisms, including internal pore clogging by contaminants, coverage of pore entrances and deposition on the membrane surface. In this paper, we present an efficient method for modelling the behaviour of a filter, which accounts for different retention ...
A. U. Krupp +2 more
openaire +4 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Reverse osmosis-based enrichment of virus in water samples: an experiment study
Zhongguo gonggong weisheng, 2023 ObjectiveTo establish a reverse osmosis technology-based method for enrichment of virus in water samples. MethodsTwo inactivated virus vaccines and two viral nucleic acid plasmids were added into simulated water samples and detected with real-time ...
Chao LIU, Ping LI, Yan PANG
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Materials Research Express, 2022 Water is a necessity for all living and non-living organisms on this planet. It is understood that clean water sources are decreasing by the day, and the rapid rise of Industries and technology has led to an increase in the release of toxic effluents ...
Utkarsh Chadha +7 more
doaj +1 more source
Nanomaterials, 2021 High-performance air filtration was the key to health protection from biological and ultrafine dust pollution. A self-supporting, three-dimensional (3D) nanofibrous membrane with curled pattern was electrospun for the filtration, of which the micro ...
Gaofeng Zheng +7 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source