Results 151 to 160 of about 1,127,226 (291)

Viscosity of concentrated mRNA solutions: Implications for downstream processing

Biotechnology Progress, EarlyView.
Abstract Messenger RNA (mRNA) therapeutics can be used to protect against infectious disease and for the treatment of cancers and genetic disorders. In order to obtain the desired therapeutic dosage, it is necessary to concentrate the mRNA to levels where the viscosity of the mRNA solutions can become significant.
Amin Javidanbardan, Fatemeh Najafi, Ziqiao Wang, Andrew L. Zydney   +3 more
wiley   +1 more source

Effect of Membrane Pore Size on Membrane Fouling of Corundum Ceramic Membrane in MBR. [PDF]

Int J Environ Res Public Health, 2023
Huang R, Pan H, Zheng X, Fan C, Si W, Bao D, Gao S, Tian J.   +7 more
europepmc   +1 more source

Application of commercial ultrafiltration membranes for protein purification by high performance countercurrent membrane purification (HPCMP)

Biotechnology Progress, EarlyView.
Abstract High performance countercurrent membrane purification (HPCMP) has emerged as a promising diffusive separation strategy for the purification of recombinant proteins and monoclonal antibodies (mAbs). However, prior studies employed dialysis membranes, which are designed for diffusive separations but have not been validated for biopharmaceutical ...
Aylin Mohammadzadehmarandi, Nate Heller, Mohammadreza Ahmadimashhadi, Jon Petrone, Nicholas Marchand, Siavash Darvishmanesh, Ka Zhang, Stefano Menegatti, Andrew L. Zydney   +8 more
wiley   +1 more source

Physics-informed machine learning for cross-study prediction of oil-water membrane fouling. [PDF]

Sci Rep
Alves CL, Weschenfelder SE, Cechinel MAP, Proner MC, de Fátima R, Moreira PM, Ambrosi A, Di Luccio M, González SYG.   +8 more
europepmc   +1 more source

Comparative analysis of membrane fouling mechanisms induced by operation modes of membrane bioreactors with aerobic granular sludge. [PDF]

Heliyon, 2023
Wang Y, Li J, Zhu J.
europepmc   +1 more source

Regenerative perfusion bioreactor for biologics production with lower COGs

Biotechnology Progress, EarlyView.
Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne, Dohyun Park, Hourieh Ahi, Jaeweon Lee, Seongkyu Yoon, Jongyoon Han   +5 more
wiley   +1 more source

Coagulation pretreatment could deteriorate reverse osmosis membrane fouling. [PDF]

Nat Commun
Ding H, Liang S, Lin W, Chen C, Gao R, Li Y, Li Y, Xiao K, Huang X.   +8 more
europepmc   +1 more source

Application of Optical Coherence Tomography (OCT) to Analyze Membrane Fouling under Intermittent Operation. [PDF]

Membranes (Basel), 2023
Lee S, Cho H, Choi Y, Lee S.
europepmc   +1 more source

Dual‐Function Electrocatalysis: Simultaneous Wastewater Remediation and Hydrogen Evolution—A Comprehensive Review

Carbon Energy, EarlyView.
Replacing the oxygen evolution reaction with the electro‐oxidation of pollutants and waste streams offers an energy‐efficient route for simultaneous hydrogen production and pollutant remediation. This review summarizes the reaction mechanisms, catalyst design principles, and emerging paired‐electrolysis strategies that govern activity, selectivity ...
Safa Al‐Yahyaey, Rashid Al‐Hajri, Ala'a H. Al‐Muhtaseb, Hussein A. Younus, Mohammed Al‐Abri   +4 more
wiley   +1 more source

Synthetic urine oversimplification results in misleading membrane fouling mechanisms in bipolar membrane electrodialysis. [PDF]

Nat Commun
Yang HR, Hu SJ, Zhang MY, Wu D, Zheng L, She Q, Yuan ZH, Zhong LJ, Zhao X, Chen Y, Liu H, Xu LJ, Liu Y.   +12 more
europepmc   +1 more source