Results 271 to 280 of about 2,200,142 (368)

Recent Advances in Enzymes and Chemoenzymatic Synthesis of Tetrasaccharide Linkage Region of Proteoglycans

open access: yesChemBioChem, Accepted Article.
Proteoglycans (PGs) play roles in many important biological events including growth factor signaling, wound repair, blood coagulation, brain development, and neural stem cell migration. As the glycosaminoglycan chain of PGs is attached to the core protein through a tetrasaccharide linkage region, it is important to decipher the intricate control of the
Po-han Lin, Xuefei Huang
wiley   +1 more source

Covalent Peptide‐Graphene Conjugates for Enhanced Cell Spreading, Osteogenic Differentiation, and Angiogenesis in Bone Defects

open access: yesChemBioChem, Accepted Article.
Traumatic bone injury is one of the most common injuries that require surgical intervention, and current treatments suffer severe drawbacks. Modern research in bone regeneration focuses on implants will support and enhance native tissue regeneration. One scaffold material that shows promise is graphene oxide (GO), a 2D nanomaterial made from oxidation ...
Michelle Elise Wolf   +4 more
wiley   +1 more source

First Steps toward the Design of Peptides that Influence the Intracellular Palmitoylation Machinery

open access: yesChemBioChem, EarlyView.
Herein, DC peptides consisting of the cell‐penetrating peptide sC18* and a Asp–His–His–Cys (DHHC) motif derived from human ZDHHC palmitoyltransferase are highlighted. DC peptides demonstrate high cellular internalization into various cellular models, exert cytotoxic effects against cancerous cells, and alter the function and localization of known ...
Katharina Stillger   +7 more
wiley   +1 more source

Catalysis in Chemical Modification of Proteins

open access: yesChemCatChem, EarlyView.
Catalytic principles of synthetic organic chemistry have been increasingly applied to chemical modification of proteins during the recent years. This review article describes how seven types of catalytic systems —electrocatalysis, photocatalysis, metal catalysis, acid catalysis, organocatalysis, supramolecular catalysis, and heterogeneous catalysis ...
Seiya Ishizawa   +4 more
wiley   +1 more source

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