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Platelet Membrane Glycoproteins
2017Platelets are small anucleate blood cells that are produced in the bone marrow from the cytoplasm of megakaryocytes. Circulating platelets are essential for primary hemostasis and also involved in pathological thrombosis. For the platelet hemostatic functions, platelet surface membrane glycoproteins are crucial to form platelet-subendothelial matrix ...
Hisashi Kato, Yoshiaki Tomiyama
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Membrane glycoprotein choreography
Current Biology, 1991It is generally understood that interactions of the integral plasma membrane proteins with the underlying cytoskeleton are responsible for many cellular processes, including cell motility, cell adhesion, cell polarity, and membrane internalization. Although a few membranecytoskeletal interactions have been defined at the molecular level, there has been
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Biological Reviews, 1968
Summary1. Although the classical models of biomembranes have emphasized the lipid and protein nature of these structures, a small quantity of carbohydrate is present as glycoprotein and glycolipid in animal cell membranes. In this article an attempt has been made to indicate that such carbohydrate materials should be considered in any complete model of
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Summary1. Although the classical models of biomembranes have emphasized the lipid and protein nature of these structures, a small quantity of carbohydrate is present as glycoprotein and glycolipid in animal cell membranes. In this article an attempt has been made to indicate that such carbohydrate materials should be considered in any complete model of
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Membrane Glycoproteins in Cryopreserved Platelets
Vox Sanguinis, 1994AbstractAlthough platelets stored by cryopreservation are effective in hemostasis, they acquire a number of functional defects during storage and preparation for transfusion. In addition to known acquired defects such as defective aggregation, decreased resistance to hypotonic shock, and disc‐spherocyte transformation, we have shown that cryopreserved ...
M, Owens +3 more
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1978
Publisher Summary This chapter discusses glycoprotein membrane enzymes individually in a sequence concentrating initially on the enzymes of general distribution, followed by brush border hydrolases and acid hydrolases of the lysosome. The chapter concentrates on two aspects of glycoprotein membrane enzymes: (1) the characterization, membrane ...
John R. Riordan, Gordon G. Forstner
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Publisher Summary This chapter discusses glycoprotein membrane enzymes individually in a sequence concentrating initially on the enzymes of general distribution, followed by brush border hydrolases and acid hydrolases of the lysosome. The chapter concentrates on two aspects of glycoprotein membrane enzymes: (1) the characterization, membrane ...
John R. Riordan, Gordon G. Forstner
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Circular dichroism of erythrocyte membrane glycoproteins
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1975The circular dichroism spectra were obtained for purified equine, human and bovine membrane glycoproteins, which have 40, 55 and 70% carbohydrate, respectively. The spectra in aqueous buffer show similar shapes, maxima and minima but somewhat different peak amplitudes. Analysis of the spectra indicated that the glycoproteins can be pictured as existing
R V, Decker, K L, Carraway
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Reprocessing of Membrane Glycoproteins
1994Newly synthesized surface glycoproteins undergo extensive processing of their N-linked oligosaccharides during transport from the endoplasmic reticulum to the cell surface (for review Kornfeld and Kornfeld 1985). The fundamental processing reactions include removal of glucose and mannose residues from Glc3Man9GlcNAc2 by glucosidases I and II and ...
R. Tauber +7 more
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Synthesis of membrane glycoproteins.
The Tokai journal of experimental and clinical medicine, 1983Glycoprotein synthesis is a central function of the endoplasmic reticulum and dolichol phosphates play an important role in the establishment of the core part of the oligosaccharide chain. Dolichol metabolism requires the cooperative action of several intracellular organelles and disturbance in the metabolism is one of the factors behind changes in ...
G, Dallner +3 more
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Model membranes bearing glycolipids and glycoproteins
Chemistry and Physics of Lipids, 1986The forces that hold cell membrane components together are non-covalent and thermodynamically favoured in aqueous media. Hence virtually any glycolipid or membrane glycoprotein might be expected to be incorporable into lipid bilayer membranes and this expectation has been borne out. In addition methods have been developed for linking lipid fragments to
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