Results 291 to 300 of about 2,200,142 (368)

First‐in‐Human Single and Multiple Ascending Dose Studies of Balinatunfib, a Small Molecule Inhibitor of TNFR1 Signaling in Healthy Participants

Clinical Pharmacology &Therapeutics, EarlyView.
Oral small molecule inhibitors of tumor necrosis factor alpha (TNFα) are emerging as attractive therapeutic agents for the treatment of various autoimmune diseases. Balinatunfib (SAR441566), a novel oral inhibitor of tumor necrosis factor receptor 1 (TNFR1) signaling, changes the configuration of the soluble TNFα (sTNFα) trimer and prevents its ...
Nassr Nassr, Faiza Rharbaoui, Dietmar Weitz, Johann Gassenhuber, Markus Rehberg, Markus Kohlmann, Fabienne Schumacher, Amel Lahmar, Andreas Kovar, Laurent Perrin, Frank‐Dietrich Wagner, Maria Wiekowski, Mai Anh Nguyen   +12 more
wiley   +1 more source

Cytomegalovirus host receptor expression in the human fetal inner ear. [PDF]

PLoS One
Grijpink LCM, van der Valk WH, van Beelen ESA, de Groot JCMJ, Locher H, Vossen ACTM.   +5 more
europepmc   +1 more source

Phospholipase PlcH is involved in the secretion of cell wall glycoproteins and contributes to the host immune response of Aspergillus fumigatus. [PDF]

mLife
Hao J, Guo Y, Zhou H, Ouyang H, Yang J, Fang W, Jin C.   +6 more
europepmc   +1 more source

Methodology of high‐dimensional flow cytometry in monitoring immune microenvironment of pituitary neuroendocrine tumors

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Characterization of the tumor immune microenvironment (TIME) of pituitary neuroendocrine tumors (PitNETs) is crucial for understanding the behavior of different types of PitNETs and identification of possible causes of their aggressiveness, rapid growth, and resistance to therapy.
Marina Yu Loguinova, Valeria V. Mazeeva, Daria V. Lisina, Elena N. Zakharova, Alyona V. Sorokina, Lilya U. Dzhemileva, Andrei Yu Grigoriev, Alexandra S. Shutova, Ekaterina A. Pigarova, Larisa K. Dzeranova, Galina A. Melnichenko, Natalia G. Mokrysheva, Sergei A. Rumiantsev, Vladimir P. Chekhonin   +13 more
wiley   +1 more source

<i>Vibrio</i> MARTX toxin binding of biantennary N-glycans at host cell surfaces. [PDF]

Sci Adv
Chen J, Goerdeler F, Jaroentomeechai T, Hernandez FXS, Wang X, Clausen H, Narimatsu Y, Satchell KJF.   +7 more
europepmc   +1 more source

How herpes is assembled. [PDF]

Elife
Zyla DS.
europepmc   +1 more source

N-Glycosylation Modification of Fzd4 Is Essential for the Fzd4-Wnt-β-Catenin Signalling Axis. [PDF]

J Cell Mol Med
Ji T, Li X, Li J, Wang G.
europepmc   +1 more source

Herpes simplex virus 1 envelope glycoprotein C shields glycoprotein D to protect virions from entry-blocking antibodies. [PDF]

J Virol
Hull MA, Pritchard SM, Nicola AV.
europepmc   +1 more source

Glycolipids, glycoproteins and membrane fusion.

Indian journal of biochemistry & biophysics, 1988
openaire   +2 more sources

Enhanced Adhesion of Mildly Positively Charged Vesicles to Endothelial Cells with Shed Glycocalyx. [PDF]

ACS Omega
Sirch MM, Wörle D, Huber MG, Westerhausen C.   +3 more
europepmc   +1 more source