Results 131 to 140 of about 2,227,411 (293)

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

open access: yesFEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li   +7 more
wiley   +1 more source

Concentration of clarified orange juice through direct contact membrane distillation

open access: yes, 2015
The conventional unit operations employed for the concentration of fruit juices are usually thermal evaporation or osmotic membrane distillation (OMD).
Conidi C   +4 more
core  

Assessment of oil fouling by oil-membrane interaction energy analysis

open access: yes, 2018
Membrane-filtration is promising for treating the voluminous oily wastewater, especially when the oil emulsions are smaller than 20 µm. However, studies on the inevitable membrane fouling phenomenon by oil are rather scarce.
Tanudjaja, Henry Jonathan   +3 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Surface modification of 3D‐printed polycaprolactone scaffolds with silk fibroin for bone tissue engineering

open access: yesFEBS Open Bio, EarlyView.
Coating 3D‐printed PCL scaffolds with silk fibroin can improve biocompatibility and bone cell adhesion. One innovative design for tissue‐engineering scaffolds uses 3D printing technology. Here, we used polycaprolactone (PCL) filament as a biocompatible material to design a porous 3D scaffold for bone tissue engineering.
Hamed Koeini   +7 more
wiley   +1 more source

Potential effect of human chorionic gonadotropin‐induced extracellular vesicle RNAs on mouse ovarian granulosa cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the LH action in the ovary, granulosa‐cell and mouse models were stimulated by hCG, which changed RNA profiles within extracellular vesicles (EVs), and potentially hCG‐responsive EV RNAs increased the number of recipient ovarian cells. EV‐associated RNAs are potential intermediaries of hCG signaling.
Natchanok Puangjit   +6 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

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