Results 71 to 80 of about 2,227,411 (293)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Experimental and theoretical investigation of a new air gap membrane distillation module with a corrugated feed channel

open access: yes, 2020
In this study, a novel feed channel was designed and examined for an air gap membrane distillation (AGMD) module to create different geometries, aiming to improve the module's performance.
Y Elhenawy NASElminshawy   +3 more
core   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Separation efficiency of livestock manure biogas by membrane

open access: yesTropical Agricultural Research, 2015
In this study, biogas generated from the anaerobic digestion of animal manure was purified and separated and the hollow fiber membrane was prepared by the phase separation of cellulose triacetate (CTA) method to separate the biogas.
Jong Eon Kim   +3 more
doaj   +1 more source

Energy efficiency of hollow fibre membrane module in the forward osmosis seawater desalination process [PDF]

open access: yes, 2019
© 2019 This study provided new insights regarding the energy efficiency of hollow fibre forward osmosis modules for seawater desalination; and as a consequence an approach was developed to improve the process performance. Previous analysis overlooked the
Altaee, A   +7 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Performance Investigation of O-Ring Vacuum Membrane Distillation Module for Water Desalination

open access: yesJournal of Chemistry, 2016
A new O-ring flat sheet membrane module design was used to investigate the performance of Vacuum Membrane Distillation (VMD) for water desalination using two commercial polytetrafluoroethylene (PTFE) and polyvinylidene fluoride (PVDF) flat sheet ...
Adnan Alhathal Alanezi   +4 more
doaj   +1 more source

Performance Analysis of Membrane Separation Process for Water and Heat Recovery from Flue Gas

open access: yesChemical Engineering Transactions, 2020
Membrane separation process can simultaneously recover water vapour and waste heat from flue gases, which has great potential for water and energy savings.
Chenhui Jia   +3 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

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