Results 1 to 10 of about 434,152 (282)
Synaptic NMDA receptor activity at resting membrane potentials [PDF]
Frontiers in Cellular Neuroscience, 2022 NMDA receptors (NMDARs) are crucial for glutamatergic synaptic signaling in the mammalian central nervous system. When activated by glutamate and glycine/D-serine, the NMDAR ion channel can open, but current flux is further regulated by voltage-dependent
Delia N. Chiu, Brett C. Carter
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Effects of membrane potentials on the electroporation of giant unilamellar vesicles. [PDF]
PLoS ONE, 2023 Living organisms maintain a resting membrane potential, which plays an important role in various biophysical and biological processes. In the context of medical applications, irreversible electroporation (IRE) is a non-thermal and minimally invasive ...
Md Abdul Wadud +3 more
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Membrane water for probing neuronal membrane potentials and ionic fluxes at the single cell level [PDF]
Nature Communications, 2018 Non-invasive spatiotemporal probing of electric potentials in living neurons without chemical or genetic modification provides a major advancement to neuroscience.
M. E. P. Didier +4 more
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Zebrafish fast muscle contractions avoid the mammalian requirement for voltage-gated Na+ channels. [PDF]
PLoS BiologyFast skeletal muscle fibers from zebrafish share a number of functional properties with mammalian twitch muscle fibers, making this vertebrate a precious model to investigate the pathophysiology of neuromuscular disorders.
Léa Demesmay +10 more
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Optical Mapping of Cardiomyocytes in Monolayer Derived from Induced Pluripotent Stem Cells
Cells, 2023 Optical mapping is a powerful imaging technique widely adopted to measure membrane potential changes and intracellular Ca2+ variations in excitable tissues using voltage-sensitive dyes and Ca2+ indicators, respectively.
Mohammed Djemai +3 more
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PLoS Computational Biology, 2022 Identifying plausible mechanisms for compartmentalization and accumulation of the organic intermediates of early metabolic cycles in primitive cells has been a major challenge in theories of life's origins.
Amir Akbari, Bernhard O Palsson
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On the accuracy of cell-attached current-clamp recordings from cortical neurons
Frontiers in Molecular Neuroscience, 2022 Cell-attached current-clamp (CA/CC) recordings have been proposed to measure resting membrane potential and synaptic/agonist responses in neurons without disrupting the cell membrane, thus avoiding the intracellular dialysis that occurs in conventional ...
Alina Vazetdinova +8 more
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BRANEart: Identify Stability Strength and Weakness Regions in Membrane Proteins
Frontiers in Bioinformatics, 2021 Understanding the role of stability strengths and weaknesses in proteins is a key objective for rationalizing their dynamical and functional properties such as conformational changes, catalytic activity, and protein-protein and protein-ligand ...
Sankar Basu +7 more
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Frontiers in Physiology, 2022 The receptor potentials of taste receptor cells remain unclear. Here, we demonstrate that taste receptor cells generate oscillating depolarization (n = 7) with action potentials in response to sweet, bitter, umami, and salty taste substances.
Yoshiki Nakao +2 more
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Event-Based Update of Synapses in Voltage-Based Learning Rules
Frontiers in Neuroinformatics, 2021 Due to the point-like nature of neuronal spiking, efficient neural network simulators often employ event-based simulation schemes for synapses. Yet many types of synaptic plasticity rely on the membrane potential of the postsynaptic cell as a third ...
Jonas Stapmanns +9 more
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