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Synaptic NMDA receptor activity at resting membrane potentials [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2022
NMDA receptors (NMDARs) are crucial for glutamatergic synaptic signaling in the mammalian central nervous system. When activated by glutamate and glycine/D-serine, the NMDAR ion channel can open, but current flux is further regulated by voltage-dependent
Delia N. Chiu, Brett C. Carter
doaj   +2 more sources

Effects of membrane potentials on the electroporation of giant unilamellar vesicles. [PDF]

open access: yesPLoS ONE, 2023
Living organisms maintain a resting membrane potential, which plays an important role in various biophysical and biological processes. In the context of medical applications, irreversible electroporation (IRE) is a non-thermal and minimally invasive ...
Md Abdul Wadud   +3 more
doaj   +2 more sources

Membrane water for probing neuronal membrane potentials and ionic fluxes at the single cell level [PDF]

open access: yesNature Communications, 2018
Non-invasive spatiotemporal probing of electric potentials in living neurons without chemical or genetic modification provides a major advancement to neuroscience.
M. E. P. Didier   +4 more
doaj   +2 more sources

MEMBRANE POTENTIALS AND CATAPHORETIC POTENTIALS OF PROTEINS [PDF]

open access: yesJournal of General Physiology, 1923
1. It has been shown in preceding publications that the membrane potentials of protein solutions or gels are determined by differences in the concentration of a common ion (e.g. hydrogen ion) inside a protein solution or protein gel and an outside aqueous solution free from protein, and that the membrane potentials can be calculated with a good degree ...
J Loeb, Loeb Jacques
openaire   +4 more sources

How Far Do Membrane Potentials Extend in Space Beyond the Membrane Itself?

open access: yesInternational Journal of Electrochemical Science, 2010
The dynamic Nernst-Planck-Poisson equations are used to describe a model system in which an infinitesimal partially permeable membrane separates two different ionic solutions which extend freely in either direction.
Kristopher R. Ward   +2 more
doaj   +3 more sources

Conserved Kir channel mechanisms governing intrinsic excitability in human and rodent parvalbumin neurons [PDF]

open access: yesCommunications Biology
Human cortical interneurons differ from their rodent counterparts in intrinsic membrane properties, yet the mechanisms regulating excitability across physiologically relevant membrane potentials remain poorly defined.
Szabina Furdan   +20 more
doaj   +2 more sources

Optical Mapping of Cardiomyocytes in Monolayer Derived from Induced Pluripotent Stem Cells

open access: yesCells, 2023
Optical mapping is a powerful imaging technique widely adopted to measure membrane potential changes and intracellular Ca2+ variations in excitable tissues using voltage-sensitive dyes and Ca2+ indicators, respectively.
Mohammed Djemai   +3 more
doaj   +1 more source

Positively charged mineral surfaces promoted the accumulation of organic intermediates at the origin of metabolism.

open access: yesPLoS Computational Biology, 2022
Identifying plausible mechanisms for compartmentalization and accumulation of the organic intermediates of early metabolic cycles in primitive cells has been a major challenge in theories of life's origins.
Amir Akbari, Bernhard O Palsson
doaj   +1 more source

Mitochondrial membrane potential [PDF]

open access: yesAnalytical Biochemistry, 2018
The mitochondrial membrane potential (ΔΨm) generated by proton pumps (Complexes I, III and IV) is an essential component in the process of energy storage during oxidative phosphorylation. Together with the proton gradient (ΔpH), ΔΨm forms the transmembrane potential of hydrogen ions which is harnessed to make ATP.
Ljubava D, Zorova   +11 more
openaire   +2 more sources

On the accuracy of cell-attached current-clamp recordings from cortical neurons

open access: yesFrontiers in Molecular Neuroscience, 2022
Cell-attached current-clamp (CA/CC) recordings have been proposed to measure resting membrane potential and synaptic/agonist responses in neurons without disrupting the cell membrane, thus avoiding the intracellular dialysis that occurs in conventional ...
Alina Vazetdinova   +8 more
doaj   +1 more source

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