Results 11 to 20 of about 442,263 (324)

BRANEart: Identify Stability Strength and Weakness Regions in Membrane Proteins

Frontiers in Bioinformatics, 2021
Understanding the role of stability strengths and weaknesses in proteins is a key objective for rationalizing their dynamical and functional properties such as conformational changes, catalytic activity, and protein-protein and protein-ligand ...
Sankar Basu, Sankar Basu, Simon S. Assaf, Fabian Teheux, Marianne Rooman, Marianne Rooman, Fabrizio Pucci, Fabrizio Pucci   +7 more
doaj   +1 more source

A space-fractional cable equation for the propagation of action potentials in myelinated neurons [PDF]

, 2020
Myelinated neurons are characterized by the presence of myelin, a multilaminated wrapping around the axons formed by specialized neuroglial cells. Myelin acts as an electrical insulator and therefore, in myelinated neurons, the action potentials do not ...
Drapaca, Corina S., Ozdemir, Sahin, Proctor, Elizabeth A.   +2 more
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Taste Receptor Cells Generate Oscillating Receptor Potentials by Activating G Protein-Coupled Taste Receptors

Frontiers in Physiology, 2022
The receptor potentials of taste receptor cells remain unclear. Here, we demonstrate that taste receptor cells generate oscillating depolarization (n = 7) with action potentials in response to sweet, bitter, umami, and salty taste substances.
Yoshiki Nakao, Katsumi Tateno, Yoshitaka Ohtubo   +2 more
doaj   +1 more source

The microbiologist’s guide to membrane potential dynamics [PDF]

, 2020
All cellular membranes have the functionality of generating and maintaining the gradients of electrical and electrochemical potentials. Such potentials were generally thought to be an essential but homeostatic contributor to complex bacterial behaviors ...
Asally, Munehiro, Benarroch, Jonatan M.
core   +1 more source

Event-Based Update of Synapses in Voltage-Based Learning Rules

Frontiers in Neuroinformatics, 2021
Due to the point-like nature of neuronal spiking, efficient neural network simulators often employ event-based simulation schemes for synapses. Yet many types of synaptic plasticity rely on the membrane potential of the postsynaptic cell as a third ...
Jonas Stapmanns, Jonas Stapmanns, Jan Hahne, Moritz Helias, Moritz Helias, Matthias Bolten, Markus Diesmann, Markus Diesmann, Markus Diesmann, David Dahmen   +9 more
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Effect of Porosity and Concentration Polarization on Electrolyte Diffusive Transport Parameters through Ceramic Membranes with Similar Nanopore Size

Nanomaterials, 2014
Diffusive transport through nanoporous alumina membranes (NPAMs) produced by the two-step anodization method, with similar pore size but different porosity, is studied by analyzing membrane potential measured with NaCl solutions at different ...
Virginia Romero, Victor Vega, Javier García, Victor M. Prida, Blanca Hernando, Juana Benavente   +5 more
doaj   +1 more source

Geometry based dynamic modeling of the neuron-electrode interface [PDF]

, 2000
A dynamic model of the neuron-electrode interface is presented which is based on the interface geometry and the electrical properties of the neuronal membrane. The model is used to compute the potential at the electrode and the local membrane potentials.
Buitenweg, J.R., Marani, E., Rutten, W.L.C.   +2 more
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A Protocol for Transverse Cardiac Slicing and Optical Mapping in Murine Heart

Frontiers in Physiology, 2019
Thin living tissue slices have recently emerged as a new tissue model for cardiac electrophysiological research. Slices can be produced from human cardiac tissue, in addition to small and large mammalian hearts, representing a powerful in vitro model ...
S. He, Q. Wen, C. O’Shea, R. Mu-u-min, K. Kou, A. Grassam-Rowe, Y. Liu, Z. Fan, X. Tan, X. Ou, P. Camelliti, D. Pavlovic, M. Lei, M. Lei   +13 more
doaj   +1 more source

KCNQ and KCNE Isoform-Dependent Pharmacology Rationalizes Native American Dual Use of Specific Plants as Both Analgesics and Gastrointestinal Therapeutics

Frontiers in Physiology, 2021
Indigenous peoples of the Americas are proficient in botanical medicine. KCNQ family voltage-gated potassium (Kv) channels are sensitive to a variety of ligands, including plant metabolites.
Geoffrey W. Abbott, Kaitlyn E. Redford, Ryan F. Yoshimura, Rían W. Manville, Luiz Moreira, Kevin Tran, Grey Arena, Alexandra Kookootsedes, Emma Lasky, Elliot Gunnison   +9 more
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Presynaptic actions of 4-Aminopyridine and γ-aminobutyric acid on rat sympathetic ganglia in vitro [PDF]

, 1980
Responses to bath-applications of 4-aminopyridine (4-AP) and -aminobutyric acid (GABA) were recorded intracellularly from neurones in the rat isolated superior cervical ganglion.
A Nistri, A Tokunaga, B Hue, B Katz, C Nicholson, CL Schauf, DA Brown, DA Brown, DA Brown, DA Brown, DA McAfee, DI Wallis, E Jankowska, E Kato, E Kato, G. ten Bruggencate, H Lundh, H Lundh, H Meves, IG Marshall, JE Heuser, JZ Yeh, JZ Yeh, K Golenhofen, M Lemeignan, M Lemeignan, M. Galvan, NG Bowery, P. Grafe, PR Adams, R Llinás, SY Chiu, T Brismar, T Yanagisawa, W Ulbricht, WC Bowman, WW Douglas   +36 more
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