Results 11 to 20 of about 12,112,951 (393)

The “Funny” Current (I_f) Inhibition by Ivabradine at Membrane Potentials Encompassing Spontaneous Depolarization in Pacemaker Cells

Molecules, 2012
Recent clinical trials have shown that ivabradine (IVA), a drug that inhibits the funny current (<em>I_f</em>) in isolated sinoatrial nodal cells (SANC), decreases heart rate and reduces morbidity and mortality in ...
Yael Yaniv, Victor A. Maltsev, Bruce D. Ziman, Harold A. Spurgeon, Edward G. Lakatta   +4 more
doaj   +2 more sources

Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent. [PDF]

EMBO J, 2019
The mitochondrial membrane potential (ΔΨm) is the main driver of oxidative phosphorylation (OXPHOS). The inner mitochondrial membrane (IMM), consisting of cristae and inner boundary membranes (IBM), is considered to carry a uniform ΔΨm.
Wolf DM, Segawa M, Kondadi AK, Anand R, Bailey ST, Reichert AS, van der Bliek AM, Shackelford DB, Liesa M, Shirihai OS.   +9 more
europepmc   +2 more sources

Cellular Membrane Potentials and Contractility of Normal Rat Atrium and the Effects of Temperature, Tension and Stimulus Frequency [PDF]

Circulation Research, 1955
Philip B. Hollander, J. Webb
openalex   +2 more sources

SODIUM, POTASSIUM, AND CHLORIDE TRANSPORT AND MEMBRANE POTENTIALS IN VALONIA VENTRICOSA

, 1966
1. The marine alga Valonia ventricosa regulates its ionic content by means of several ion pumps. An active extrusion of Na+ and probably an active uptake of K+ occur at the plasmalemma.
John Gutknecht
openalex   +3 more sources

Taste Receptor Cells Generate Oscillating Receptor Potentials by Activating G Protein-Coupled Taste Receptors

Frontiers in Physiology, 2022
The receptor potentials of taste receptor cells remain unclear. Here, we demonstrate that taste receptor cells generate oscillating depolarization (n = 7) with action potentials in response to sweet, bitter, umami, and salty taste substances.
Yoshiki Nakao, Katsumi Tateno, Yoshitaka Ohtubo   +2 more
doaj   +1 more source

The mechanism of oscillatory activity at low membrane potentials in cardiac Purkinje fibres

Journal of Physiology, 1969
O Hauswirth, Denis Noble, Richard W. Tsien   +2 more
openalex   +3 more sources

Event-Based Update of Synapses in Voltage-Based Learning Rules

Frontiers in Neuroinformatics, 2021
Due to the point-like nature of neuronal spiking, efficient neural network simulators often employ event-based simulation schemes for synapses. Yet many types of synaptic plasticity rely on the membrane potential of the postsynaptic cell as a third ...
Jonas Stapmanns, Jonas Stapmanns, Jan Hahne, Moritz Helias, Moritz Helias, Matthias Bolten, Markus Diesmann, Markus Diesmann, Markus Diesmann, David Dahmen   +9 more
doaj   +1 more source

Membrane potential and cancer progression [PDF]

Frontiers in Physiology, 2013
Membrane potential (Vm ), the voltage across the plasma membrane, arises because of the presence of different ion channels/transporters with specific ion selectivity and permeability. Vm is a key biophysical signal in non-excitable cells, modulating important cellular activities, such as proliferation and differentiation.
Yang, Ming, Brackenbury, William J
openaire   +5 more sources

KCNQ and KCNE Isoform-Dependent Pharmacology Rationalizes Native American Dual Use of Specific Plants as Both Analgesics and Gastrointestinal Therapeutics

Frontiers in Physiology, 2021
Indigenous peoples of the Americas are proficient in botanical medicine. KCNQ family voltage-gated potassium (Kv) channels are sensitive to a variety of ligands, including plant metabolites.
Geoffrey W. Abbott, Kaitlyn E. Redford, Ryan F. Yoshimura, Rían W. Manville, Luiz Moreira, Kevin Tran, Grey Arena, Alexandra Kookootsedes, Emma Lasky, Elliot Gunnison   +9 more
doaj   +1 more source

The Potential across a Membrane. [PDF]

Acta Chemica Scandinavica, 1968
Tormod Førland, Lars Uno Thulin, Sven Westman, Torbjörn Norin   +3 more
openalex   +3 more sources