Results 241 to 250 of about 442,263 (324)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Membrane Potential Evaluation of Platelets from Chronic Myeloproliferative Neoplasms and Thrombosis Patients

Clara Matei, Viola Maria Popov, Mircea Bogdan Matei, Eszter Kovács, Mihaela G. Moisescu, Tudor Savopol   +5 more
openalex   +1 more source

Model of membrane-potential fluctuations [PDF]

, 2016
Miraslau L. Barabash, Aneta Stefanovska
openalex  

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Cold Shock Compromises the Electrically Mediated Block to Polyspermy in Lytechinus variegatus Eggs. [PDF]

Mol Reprod Dev
Ivonnet PI, Chambers L, Künzi L, Garcia G.   +3 more
europepmc   +1 more source

A red-emitting carborhodamine for monitoring and measuring membrane potential [PDF]

Anneliese M. M. Gest, Julia R. Lazzari-Dean, Gloria Ortiz, Susanna K. Yaeger-Weiss, Steven Boggess, Evan W. Miller   +5 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Autophagy-dependent modulation of ER calcium release drives KCNMA1/BKCa signaling and seizure susceptibility. [PDF]

Autophagy
Kochlamazashvili G, Kuijpers M.
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Predicting neural responses to intra- and extra-cranial electric brain stimulation by means of the reciprocity theorem. [PDF]

PLoS Comput Biol
Ness TV, Koch C, Einevoll GT.
europepmc   +1 more source